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Raltegravir and darunavir

Common Questions and Answers about Raltegravir and darunavir

isentress

Avatar f tn However, after 2013, three-drug regimen consisting of a nucleoside reverse-transcriptase inhibitor (NTRI), (tenofovir plus emtricitabine), along with a third drug, either an integrase strand transfer inhibitor, raltegravir or a boosted protease inhibitor, darunavir/ritonavir is recommended for PEP. Ideally, NTRI is an important component of the regimen because if HIV infects a cell, it first attaches to and fuses with the host cell.
Avatar n tn A 12 years old girl had a blood transfusion with hiv blood, she took PEP( tenofovir, emtricitabine, ritonavir-boosted darunavir (subsequently changed to lopinavir) and raltegravir) after 24 hours and had these PEP for three months. This girl also has cssr5 dna which is a dna that hard to infect hiv. After 8 months, she had a negative result on HIV RNA and HIV ag/ab test. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226216/).
Avatar f tn the reason why i did not take one more pill is that i believed cumulative plasma levels of raltegravir at day 22 May still exists in the circulation and thus i continued my regular dose just not to take second time double dose for raltegravir in case of i drank it through water. However i really do not remember and i also did not see any pills around. Thank you very much for your kind response.
Avatar f tn combining emtricitabine and tenofovir from the NRTI class, and raltegravir, from the integrase inhibitor class. There ARE alternative drugs available and possibly in Thailand they use lamivudine in place of raltegravir. I am definitely NOT a chemist, so I can't tell you for sure if the combination you're taking is appropriate. You should discuss your concerns with the doctor who prescribed PEP or a pharmacist/chemist. I wish you the best.
446474 tn?1446347682 * Boceprevir reduced average trough concentrations of ritonavir-boosted atazanavir (Reyataz), lopinavir (Kaletra), and darunavir (Prezista) by 49%, 43% and 59%, respectively. * On average, reductions of 25% to 36% were seen in peak concentration of the three drugs, when given with boceprevir, along with declines of 34% to 44% in exposure (area under the curve).
Avatar n tn I started PEP 2 hrs later (truvada, norvir, raltegravir, and preszita), my initial results are negative. I do not know the viral load of the patient yet, i can only pray that it is low. I know odds are 0.3% but that doesnt settle my fears, i am young and want to live a happy healthy life with KIDS! DR. please tell me if you have honstly heard of any cases like mine that have converted. I am in awe and feel like my life is totally over and ruined.
Avatar n tn I am relatively sure it did not break, but I cannot be 100% certain. Since then, he and I had talked (exchanged numbers), and he assured me he was HIV negative and had not had a partner since a negative test a few months prior. Due to my guilt and anxiety, I searched for PEP in Europe, which was IMPOSSIBLE. I eventually was able to obtain Truvada, which I started about 55hr after "exposure". I plan to take for the full 28 days.
Avatar f tn I asked the CSW if she knew her status and she said she was negative (I know that doesn’t mean anything and is almost discomforting because if she is she is most likely not on ARVs). Anyways I rushed to the hospital and was put on PEP at a maximum of 3 hours post exposure (truvada and raltegravir). I have taken the pills without missing any doses. At 3 weeks post exposure the lymph nodes in my neck swelled up slightly and I felt a tiny bit feverish.
Avatar n tn I am currently taking truvada and isentress (raltegravir) is this enough I couldn't get my prescription for dolutegravir filled...is this pep enough?
Avatar n tn m confused on the prescriptions given to me I have a 7 day dose of raltegravir and dolutegravir...thought it was supposed to be 28 days?
Avatar m tn I actually went to the clinic, got PEP (truvada 200mg and Raltegravir 400mg), also done hiv prick test which was negative. Dr was helpful and explained everything for me. He also said best thing is as u guys suggest, ask him test but also if he is clear 6 weeks back also, but that also depends on trust. On my side i don't wanna embarrass him as twice he told me not to worry.
Avatar n tn I had sex in a night club with a guy I don't know. I was very drunk and I'm not sure if we used condom or not - I've been trying to remember that moment, but it's quite impossible to trust my mind after many days. I was bottom and we had a short penetration, because I felt too much pain. But I'm not sure if there was ejaculation or not, I couldn't find the guy in the club later that night and I have no contact with him at all.
Avatar f tn I am taking Truvada and Raltegravir. Yesterday, (3 days after exposure and 2 days on PEP) I had protected sex with a female partner (I, the insertive male) and when I ejaculated I am afraid some spilled off the base of the condom. If I began PEP 24 hours after possible exposure and had protected sex with someone else on Day 2 of PEP, could I have biologically put them at risk for HIV if by any chance the ejaculate spilled off the condom?
Avatar n tn I started PEP 2 hrs later (truvada, norvir, raltegravir, and preszita), my initial results are negative. I do not know the viral load of the patient yet, i can only pray that it is low. I know odds are 0.3% but that doesnt settle my fears, i am young and want to live a happy healthy life with KIDS! DR. please tell me if you have honstly heard of any cases like mine that have converted. I am in awe and feel like my life is totally over and ruined.
Avatar f tn I'm now on week 22 of my pegasys/riba therapy and been taking suboxone ever since and never had any problems.
Avatar f tn I presume you had anal sex, because oral is not a risk. HIV is only diagnosed from a test so all your details and questions have no answers. Since you have passed 28 days, you can just take a 4th gen test for a conclusive result and all the details you mention which are just question marks will become irrelevant.
Avatar m tn Last night, I had unprotected anal sex with a transvestite sex work. I know, bad move on my part. I was on top and inside of him for only a few minutes at most. One question: How risky is this? He said he's clean, but I don't know whether to believe that. If he is HIV positive, how possible is it I contracted HIV? I rushed to the ER this morning to get PEP, but is it even necessary? And what happens if I did contract HIV and the PEP doesn't work.
Avatar f tn My OBGYN saw me last week and told me I had a mild case of BV, and that he would give me antibiotics to take twice a day for one week. He said that due to the fact that antibiotics can weaken the effects of my birth control pill (Lutera), I couldn't have sex for one week. So, my understanding was not to have sex the entire week of taking the pills. After taking my last antibiotic, the next day I had sex, and my boyfriend ejaculated inside me.
446474 tn?1446347682 The agency singled out atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor) for the new warnings and restated a warning about mixing lovastatin (Mevacor) with HIV and HCV drugs. Today's FDA safety communication follows label changes announced Tuesday that added cautions about new onset diabetes and transient memory problems for users of any of the cholesterol-lowering drugs in the statin class.
Avatar f tn I had protected sex with an ex boyfriend of mine and then in the middle of sex he took off the condom and when i realized he took it off, i jumped and stopped immediately because i got scared and it was for about 10 seconds, we then did it again for like 15 seconds without condom hours later but then put condom right back on, 6 days after i developed a rash on my lower legs and a little was above my under arms. It lasted for one day. Does this sound like early hiv symptoms?
Avatar m tn Thirteen patients were not receiving antiretroviral therapy and 37 patients were on protocol-allowed medications (tenofovir, emtricitabine, rilpivirine, raltegravir, and efavirenz). Although the inclusion criteria for patients receiving antiretroviral therapy allowed CD4+ T cell counts of greater than 100/µL, the median CD4+ T cell count was 576/µL. Overall, 98% achieved sustained virologic response at 12 weeks (SVR12; 13/13 in treatment-naive arm and 36/37 in treatment-experienced arm).
Avatar m tn Yes it's true - I'm really reaching some kind of edge again. even considered checking out this retreat but the cost was pro-hib-itive. Plus I don't really 100% believe their total philosophy, and I've already dealt with so much of what they talk about. I really do think my problems are bigger than just needing to find a life lesson, and "doing happy" etc. Lastly, I've given in - I'm sick of sleeping my life away so I've started taking....pseudoephidrine...
Avatar m tn I have been on a statin drug for about 15 years and ran for exercise until about 5 years ago and all I can conclude from my history is I have benefited from the statin drug via low cholesterol and not blockages and weight control and general high physical quality of life from the exercise. I'm 11 years younger than you, and I no longer run, but that is because of atrial fibrillation, not because of muscle damage due to anything other than age.