Besides the cost, is their truly a difference between Nexim and
Prilosec. The active components in Nexium are esomprazole magnesium and in Prilosec are Omeprazole Magnesium. Also, Nexium comes in 20 mg and 40 mg capsules and Prilosec is sold over the counter in 20 mg tablets.
My GI switched me to Nexium because Aciphex gave me terrible side effects and Protonix made my water brash symptoms ever worse.
I have tried Prilosec in the past and it didn't have much of an effect for me.