Pravastatin versus simvastatin
Common Questions and Answers about Pravastatin versus simvastatin
pravachol
There was a study done with 550 people in 1993, that looked at the differences in treatment with simvastatin versus pravastatin. Patients were put on a cholesterol-lowering diet and given one of the medications. After 18 weeks, patients given simvastatin had significantly lower total cholesterol, lower LDL, lower triglycerides, and higher HDL cholesterol levels than those who took pravastatin.
Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
s production of cytochrome P450, I am wondering about switching from simvastatin to pravastatin. That would allow me to try CBD, which appears to have minimal side-effects. I also wouldn't mind getting more than a few hours of sleep per night. That said, am I taking a risk by switching statins after three decades? I haven't been able to find any significant and update research that covers this situations. Thank you.
Two recent trials have compared the clinical outcomes of intensive lipid lowering with atorvastatin 80 mg/day and standard lowering with pravastatin 40 mg/day. In the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT) trial, patients with acute coronary artery syndromes were enrolled, and pravastatin lowered the low-density lipoprotein (LDL)-cholesterol to 2.46 mmol/l, whereas atorvastatin lowered it to 1.60 mmol/l.
It seems that the main problem was with fenofibrate and pravastatin. The level was pravastatin was greatly increased. But newer info with other statins shows no danger. Atorvastatin serum levels were actually decreased.
Jack is very correct that any individual's response can vary a lot from the norm.
> Any other natural suggestions on lowering [TG]?
I've seen studies that low carb works best, but low Glycemic Index is not that far behind.
Lisinipril is $4/month and $10 for 90 days at WalMart and many other pharmacies that have the $4 precription plan. You pay out of pocket. Simvastatin isn't on that list, but lovastatin and pravastatin are, if your doctor feels like you could try substituting one of those. Metoprolol isn't on the $4/month plan, but atenolol is. Again, maybe your doctor would be okay with changing you from metoprolol to atenolol. It's worth talking to the doc about.
Average incidence per 10 000 person-years for monotherapy with atorvastatin, pravastatin, or simvastatin was 0.44%"
Here's the link;
http://jama.ama-assn.org/content/292/21/2585.full
It is extremely rare and is not associated with Zocor (Sivastatin) more than any other statin. Statins are being found to be much safer than previously thought. For instance, it has been determined that statins help increase liver function in individuals with liver disease.
Here is an update as of Aug. 30.
I went back to the Dr.'s for a plan-of-action for the high cholesterol numbers. We decided to try Simvastatin 20mg's and I also will be adding CoQ-10 with that (my suggestion). I will be having another reading done in December to see if it brings the numbers down. He also suggested I have a Coronary Calcium Score CT done.
I had the Coronary Calcium test done the next day and received the findings today. The Total Agatston Score is 0.
9% with pravastatin (Pravachol), 14.9% with atorvastatin (Lipitor), and 18.2% with simvastatin (Zocor). And you have been on both atorvastatin (Lipitor) and pravastatin (Pravachol).
Once you stopped taking statin, the pain and aches should resolve. However, for some patients, it may take up to 2 months for symptom resolution.
t read anything that says the Zocor was responsible, just conjecture that it may be based on some Internet research. Zocor which is merely simvastatin is very safe and the incidence of side effects very low, but some will be affected differently than others.
pdf
good article about the use of fluvastatin with hcv, as regards hbv simvastatin and lovastatin are the only statins i have seen studied on hbv (among the two sim at 80mg has the strongest effect)
//www.drugs.com/sfx/pravastatin-side-effects.html#consumer_Pravastatin
Have you discussed this with your doctor? If you take other drugs and/or supplements check with your pharmacist regarding drug interactions.
I was on 40mg of Pravastatin and now am on 80mg. Is my doc just being aggressive? Or is there another reason for the big increase? I welcome any speculations.
I am a 39 year old, female. I was put on Pravastatin about 9 weeks ago as my cholesterol had gone from 190 to 225 from the previous year. I have a family history of heart disease (my father passed away after a second heart attack at 53). I was diagnosed with hypothyroidism 2 years ago and was placed on Levoxyl (75mg) and my levels have remained normal. I went to have my cholesterol checked after taking the pravastatin for 9 weeks.
m still trying to get a clarification. Anyway, the cardiologist put me on Amlodopine and Pravastatin. Now, on a daily basis it seems, my heart rate increases and beats at 90-115 bpm (normally in the mid 70s).
At the same time, I've started on a vegetarian diet to try to lower my cholesterol. To try to make sure I get enough protein, I am using a protein drink (10-14 gr protein each). I drink 1-2 of these per day.
I was put on Pravastatin about 9 weeks ago as my cholesterol had gone from 190 to 225 from the previous year. I have a family history of heart disease (my father passed away after a second heart attack at 53). I was diagnosed with hypothyroidism 2 years ago and was placed on Levoxyl (75mg) and my levels have remained normal. I went to have my cholesterol checked after taking the pravastatin for 9 weeks.
23 versus 1.17 g ml(-1)), a smaller diameter (39 versus 48 nm), but maintained particle integrity, antigenicity and ability to bind to hepatocytes. Although addition of exogenous cholesterol and cholesterol analogues restored the physical appearance of cholesterol-depleted virions, infectivity was only regained by cholesterol add-back. Infectivity of HBV produced from cell culture in the presence of inhibitors of cholesterol-synthesis is severely impaired.
I recently was prescripbed pravastatin and I notice a higher number when I test after a night of fasting in my Blood Glucose. Is there a posibility that could cause the rise.
Is it safe to take Levothyroxine at the same time as Pravastatin? Also, 2 months ago, I started to take my Levothyroxine at bedtime instead of in the morning as it is more convenient. and after a recent bloodtest my GP has reduced my Thyroxine to 75mcg instead of 100mcg. Could taking it at bedtime be the reason for this reduction? I will obviously ask my GP about this on my next visit to the surgery but would be grateful for any advice.
curious if stef2011 or studyforhope or StephenCastlecrag know whether simvastatin by itself can reduce viral load? I've read about the effects in conjunction with NUCS but I'm curious if sim is effective alone.
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