phenytoin dose conversion

Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..." It however says that initiation of Folic acid and phenytoin together is beneficial. Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.

You should tell your doctor if you experience any of these symptoms while taking phenytoin, so that your blood level of phenytoin can be measured and your dose reduced if necessary. " Also, he has had a major surgery, and will need time to recover. However, any changes need to be reported to the doctor.

Moban® brand of molindone hydrochloride contains calcium ions which interfere with the absorption of phenytoin. Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body.

My doctor Prescribed Zithromax i time dose at 2 500mg pills for an infection, and I have history of benign pvc's and pac's , while taking it i felt horrible . I felt worse than i have ever felt in life. It gave me unclear thoughts, I couldn't drive due to a foggy mind, it made my heart race and skip , i actually had to go to the ER because i thought I would die.

Something else could be affecting the change of biking velocity, or something could be affecting the effectiveness of the dose but possibly it does not have that much of an impact on the biking. In other words, do talk to her doctor about her dose, but check your assumptions about cause and effect before suggesting a change.

Thank you so much for your immediate reply doctor. My dad has been using Citilin since December 2007. Is it okay to use Citilin beyond 3 months or should it be discontinued? Also, is a tapering dose needed or stopped all of a sudden? Will it affect my dad's condition and will he get the stroke or seizures like attack again after discontinuing this medicine? After December 2007 he has not had any attack so far. Kindly let me know about this doctor. Once again, thank you very much doctor.

As there is peripheral conversion of androgens to estrogen in these patients, this is the same mechanism as polycystic ovary syndrome, PCOS. Use of drugs like Tetrahydrogestrinone Adverse effect of Phenytoin" Wikipedia - Hirsutism [Hirsutism or frazonism[1] is the excessive hairiness[2] on women[3] in those parts of the body where terminal hair does not normally occur or is minimal - for example, a beard or chest hair.

In a small study, phenytoin-induced seizures occurred most often in patients with serum phenytoin concentrations of 50 mcg/ml or higher.[393] Peripheral neuropathy, usually occurring weeks to months after drug initiation, has also been reported in patients receiving phenytoin. A single case report describes the onset of neuropathy within a few hours of drug administration.[9780] Adverse GI effects of phenytoin therapy include nausea/vomiting, constipation, abdominal pain, and anorexia.

Combining fluoxetine or paroxetine with phenytoin can also lead to increased phenytoin side effects and reduce blood levels of paroxetine. You really need to discuss the potential drug interactions with your own doctor.

Issues with Seizure Medications For some people using certain medications, generics can be a problem. This is most often a problem with medications in which even a miniscule change in dose can be ineffective or cause side effects. Dilantin (phenytoin) is one of those medications.

[23] Other causes include drug use (e.g., phenytoin, rifampicin [rifampin], carbamazepine, barbiturates) and assay error when interfering substances are present.

s temp protocol calls for timed released T3 doses that are increased by 15mcg per day up to a set dose and then back down by 15mcg per day until the dose reaches zero. This is supposed to reset my temp and hopefully make me feel much better. The cycling isn't supposed to continue for more than a couple of months after which the body temp should remain normal. Hopefully. I am a 62 year old retired teacher. I have struggled with migraines since I was 9 years old, depression since I was 14.

My doctor reduced me to the above dose and its going terribly. The conversion for the fent for that dose is 50 to 75Mcg. My dr said to try changing the patch every 2 instead of every 3. My insurance won’t pay for this non-standard dose. Idk what to do. I’m in constant pain, sweating crazy - i’m in a nightmare.

Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..

Hello AB, welcome to the medhelp forum. Phenytoin can cause certain side effects like dizziness and mental confusion. Some people may also manifest incoordinate movements. Weight gain is not a documented side effect. It could be related to your alcohol consumption or wrong dietary habits and lack of exercise. An occasional one or two drink may be fine but moderate or large amount can cause significant increases in blood levels of phenytoin due to induction of hepatic enzymes.

So goolarra is correct that your new dose is low. Just be aware of how much of a reduction the new dose represents and the likelihood of degradation in your symptoms. Which leads me to the question: what is the cause for the change in meds? If it was because of you still having hypo symptoms, then I see little risk in switching to a full grain of Armour, but do it in two stages. That way you should have the best of both possible outcomes.

http://www.globalrph.com/narcotic.

Our family is desperate to help our 14 year old daughter who has a conversion disorder accompanied by depression & severe anxiety. Her case seems to be unique for a number of reason that I can expand on if anyone out there needs more information. Our child has been doing very well once we finally found the medication Lexapro. She was a year into taking 30mg daily plus Clonepin (.25mg 2x daily) and doing very well. Recently, she started going down hill.

The diagnosis was hypo-poor conversion. Never mentioned hypothyroidism however, poor conversion on the side of hypothyroidism. Thanks for comment. Does any of this make sense?

I was on it for only one and a half years--after seizures were recorded in the EMU during my presurgical workup they dumped me on a high dose, since you can start off on a high dose--and I have osteopenia, primarily on my upper femur on both sides. As I only recently learned, dilantin is especially bad for premenopausal women (not good for anyone, of course) even if you're on it for only a year, for example.

During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.

Phenytoin dose conversion

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