Phenytoin dose
Common Questions and Answers about Phenytoin dose
dilantin
Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..."
It however says that initiation of Folic acid and phenytoin together is beneficial.
Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
Moban® brand of molindone hydrochloride contains calcium ions which interfere with the absorption of phenytoin. Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm
Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body.
Thank you so much for your immediate reply doctor. My dad has been using Citilin since December 2007. Is it okay to use Citilin beyond 3 months or should it be discontinued? Also, is a tapering dose needed or stopped all of a sudden? Will it affect my dad's condition and will he get the stroke or seizures like attack again after discontinuing this medicine? After December 2007 he has not had any attack so far.
Kindly let me know about this doctor. Once again, thank you very much doctor.
In a small study, phenytoin-induced seizures occurred most often in patients with serum phenytoin concentrations of 50 mcg/ml or higher.[393] Peripheral neuropathy, usually occurring weeks to months after drug initiation, has also been reported in patients receiving phenytoin. A single case report describes the onset of neuropathy within a few hours of drug administration.[9780]
Adverse GI effects of phenytoin therapy include nausea/vomiting, constipation, abdominal pain, and anorexia.
Issues with Seizure Medications
For some people using certain medications, generics can be a problem. This is most often a problem with medications in which even a miniscule change in dose can be ineffective or cause side effects. Dilantin (phenytoin) is one of those medications.
Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..
Hello AB, welcome to the medhelp forum. Phenytoin can cause certain side effects like dizziness and mental confusion. Some people may also manifest incoordinate movements. Weight gain is not a documented side effect. It could be related to your alcohol consumption or wrong dietary habits and lack of exercise. An occasional one or two drink may be fine but moderate or large amount can cause significant increases in blood levels of phenytoin due to induction of hepatic enzymes.
I was on it for only one and a half years--after seizures were recorded in the EMU during my presurgical workup they dumped me on a high dose, since you can start off on a high dose--and I have osteopenia, primarily on my upper femur on both sides. As I only recently learned, dilantin is especially bad for premenopausal women (not good for anyone, of course) even if you're on it for only a year, for example.
During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.
Well Keppra is the most commonly used anti-seizure medication in a setting of TBI. Often the right dose and timing adjustment helps. Symptoms in hospital may not have been due to Kreppa, and your mother may now be stronger and adjust to Kreppa.
However, you can discuss with her neurologist and ask for a change. Another drug which is commonly used in this setting is phenytoin or Dilantin. Maybe you can start this with your mother, but this also has side effects and hence may not suit her.
The estimates cited apply primarily to patients who are not taking drugs that affect hepatic metabolizing enzyme systems. For example, patients taking enzyme-inducing antiepileptic drugs (carbamazepine, phenytoin, and phenobarbital) will clear valproate more rapidly. Because of these changes in valproate clearance, monitoring of antiepileptic concentrations should be intensified whenever concomitant antiepileptics are introduced or withdrawn. ......
Hi,
What tests were done previously? Eptoin contains phenytoin which is used to control seizures. SIde effects are usually dose-related and include nystagmus, decreased coordination, and mental confusion, dizziness, insomnia, and headaches. You can read more about this through this link:
http://www.rxlist.com/dilantin-drug.htm
Take care and keep us posted.
Doctors shifted her to recovery room with oxygen mask and loaded her with Phenytoin thru IV. Then after 2 days, she was shifted to tablet dose of Eptoin 100 mg thrice a day and she is still continuing with it.
Before release from the hospital, the Neurologist performed an MRI, which came out normal. Also, my wife carries no history of seizures.
please help me:- upto what time should my wife continue with the dose?? and what could be the possible causes of this post partum seizure??
Phenytoin (Dilantin et al) works best with me. It's off patent and about 70 years on the market. Low doses best. These repetitive thoughts are a brain electrical problem (inappropriate electrical activity), and while not as intense a problem as epilepsy, they can be treated the same way.
I take 50 - 100 mg as a dose and it smoothes those intrusions and does NOT make me tired or have noticeable side effects except feeling normal.
Addition of other antiepileptic drugs like phenytoin,lamotrigene and sedatives will be helpful for controll of his night symptoms.
A few weeks ago I woke up with yellow crust on the corner of my lips and it went away in 2 days, and today I woke up and it's in the exact same spot again except a little more then before. It doesn't hurt or itch, it feels like my lips are very very dry. I don't smoke, I have grandmal seizures and my medication is phenytoin and kepra but I didn't read anywhere that would be a side effect so I'm worried this could be a STD or something.
The efficacy of oral hypoglycemic agents and insulin may be diminished by certain drugs, including thiazides and other diuretics, corticosteroids, estrogens, progestins, thyroid hormones, human growth hormone, phenothiazines, atypical antipsychotics, sympathomimetic amines, protease inhibitors, phenytoin, clozapine, megestrol, danazol, isoniazid, asparaginase, pegaspargase, diazoxide, temsirolimus, as well as pharmacologic dosages of nicotinic acid and adrenocorticotropic agents.
drugs like gabapentin, phenytoin are used for hemifacial spasm. Other options are botulinum injections and microvascular decompression surgery. Hope this helps. Take care.
my daughter has had 2 surgeries for pituiatry tumour, radiotherapy, she still has remnant tumour, (Acromegaly) but also has facial ear and neck pain, which prof says is because tumour is pressing on trigeminal nerve, tried amytrplin, never worked, 3 weeks ago prof put her on Pregabalin, small dose then up to 300 a day, within a few days of upping the dose, she has been in more pain than ever, crying, agitated, and said she thought she had pain before, but now this is unbearable, they have told
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