9 people reported to have side effects when taking Niacin
And Niacinamide, Indocyanine Green. Among them, 2 people (22.22%) have Mania.
niacin belongs to what is called antidepressant vitamins
http://www.antidepressant.com/antidepressant-vitamins.html
As a rule any antidepressant, whether vitamins, St John wort, etc...doesn't suit bipolars. in Bipoarity one has to take care as he walks and watch out where your legs go, very tricky indeed and not easy at all.