neupogen injection filgrastim

Many people on TX have had their white blood cell count go too low and they have had to take an additional injection called Neupogen. Some docs do it that way instead of reducing the treatment meds. Be sure to ask about it to see what his/her opinion is on it.

Do any of you have information about any long term side effects if you had Neupogen for 40 weeks?

Neulasta is a peglated version of Neupogen which is also know as filgrastim. It's used to stimulate production of neutrophils, a component of whilte blood cells. It can be taken less often than regular 'ol Neupogen. I found it rougher than Neupgen in that it had some side effects, mainly bone pain. I found Neupogen to be side-less. Aranesp is Darbepoetin Alfa which is like Procrit (epo). It is also taken less often than Procrit.

t understand. Why would you move the interferon injection rather than the neupogen injection? Your ANC at 700 is not alarmingly low so there isn't a need to favour neupogen over interferon with numbers like that. I don't know that the 2 day break between neupogen and interferon is a requirement as much as it is a recommendation. Why not move your neupogen injection schedule instead?

Several people here have used it. Actually, what gets whacked is a component of the WBC call neutrophils - sometime referred absolute neutrophils or ANCs. These are a separate line item on a CBC report. Docs invoke the use of Neupogen at at different levels. I found the use of Neup to be a non-event, no side effects. Others expereince bone pain and injection site soreness. It's much better to use Neupogen than to reduce the dose of the Peg.

Are you saying your mother in law has Leukemia? Filgastin or Neupogen is used for that. I don't know of other uses for it. She can't get it in the Philippines? If you can get a prescription from her doctor perhaps you can get it from a pharmacy here. Have a talk with a pharmacist here at one of the stores like Rite Aid, CVS any of those and see if they allow that.

Interferon can cause a condition called ‘neutropenia’ or the suppression of white blood cells necessary to fight infection. In some countries, the drug Neupogen (filgrastim) is available to combat this, and to keep patients on full dose HCV meds. Filgrastim and PEG-filgrastim are relatively expensive; and they might not be available in all areas.

HI ALL,HOPING U CAN HELP ME OUT WITH WHERE TO FIND/BUY MEDS LIKE NEUPOGEN FOR LOW WBC,IV HAD LOTS OF TROUBLE WITH LOW WBC AND MY DOC SAID AUSTRALIA HAS NOT APPROVED IT. IM AN AUSSIE AND HOPING SOME1 KNOWS OF WHERE TO GET THIS STUFF,OR ANYTHING THAT WILL HELP.IV HAD MY DOSE LOWERED AND IT SHATTERS ME COS MY CHANCES WOULD BE MUCH HIGHER WITH FULL DOSE OF INTERFERON. I DONT CARE WHAT IT COSTS I JUST WANT TO BRING MY WBC UP COS IV HAD SO MANY INFECTIONS AND FLUES ETC.

Yes, Neulasta is the pegylated version of Neupogen. A polyethylene glycol molecule or (“PEG”) is added to enlarge the Filgrastim molecule (Neupogen), thereby extending its half-life and causing it to be removed more slowly from the body. I don't know what the dosage requirements are for Neulasta but it is not taken as often as Neupogen.

You can discuss ‘Neupogen (filgrastim) with the doc; this is a GCSF drug that stimulates bone marrow production of white cells. It is generally initiated when absolute neutrofils reach .500 or that vicinity; some docs allow closer to .350, depending on occupation and other matters.

Neulasta® (pegfilgrastim) or NEUPOGEN® (Filgrastim) may reduce your chance of getting an infection, but it does not prevent all infections. An infection can happen anytime your neutrophil counts are low. Look for signs of infection, such as fever, chills, rash, sore throat, diarrhea, or redness, swelling, or pain around a cut or sore. If you have any of these signs, contact your health care professional immediately. http://www.neulasta.com/starting-chemo-with-neulasta/about-neulasta-neupogen.

NEUPOGEN® ( Filgrastim ) Program is designed to assist those patients who are medically indigent (patients may be uninsured or underinsured). Eligibility is based on patient's insurance status and income level.

Neulasta is the expensive pegylated counterpart of neupogen. Same drug (filgrastim). Otherwise all you can do is reduce the interferon and it's generally considered better not to do that before you've cleared the virus. I don't know of any ways to reduce your risk of infection. What are you thinking of when you say that, please?

This is called a subcutaneous injection. The best injection sites are the abdomen and the front or side of the thighs. Change the injection site each time you inject to avoid soreness at any one site. For best results, you should inject Neupogen at about the same time each day. How to inject Always follow the instructions of your doctor, pharmacist or nurse - they may be different from those below.

I had itching & rashes which last for not more than 30 min and comes only once in a day, after 3-4 days of stopping neupogen. It's very mild and goes away quickly. Should I consult to doctor or it will goes away by time. Need your suggestions.

Congratulations on being UND since week 4...that is a huge success! As far as your white blood cell count, is the injection that your doctor is giving you Neupogen? When the white count goes low to a certain point, the options are to reduce the treatment meds (which you don't want to have to do) or add an injection (Neupogen). If Neupogen is what your doc is giving you, then you are on the right track.

I believe neupogen lasts about a week. Neulasta is the same drug as neupogen (filgrastim) but is pegylated to keep it working on the bone marrow longer. Insurance paid for mine with a $100 co-pay. I cleared early and kept getting my peginterferon reduced for low platelets. I was freaked out at first to be dose-reduced. I remained clear regardless of the reduction and the study team did not seem to think it was a big deal. They were pretty worked up over keeping the riba up to full dose.

I take my chemo treatment on Friday morning and do not get the Neulasta injection until Mon. morning. Is there a problem by waiting this long for the injection?

28, I had to take 300 mcg once a week for the remainder of treatment. the 300 mcg injection were $525 usd per injection pre insurance. Most doctors will start neupogen when anc is between .3 -.5 I used 40,000 unit procrit injections once weekly when my hgb dropped drastically and after a month the dose was increased to every 4-5 days. The cost for procrit was about $725 USD per 40,000 units pre insurance. Procrit is generally prescribed when hgb reaches 10 g/dl or below.

The recommended starting dose of Neupogen is 5 mcg/kg/day‚ administered as a single daily injection by SC bolus injection, by short IV infusion (15 to 30 minutes)‚ or by continuous SC or continuous IV infusion. A CBC and platelet count should be obtained before instituting Neupogen therapy‚ and monitored twice weekly during therapy. Doses may be increased in increments of 5 mcg/kg for each chemotherapy cycle‚ according to the duration and severity of the ANC nadir.

The neupogen makes me feel so bad. for about 2.5 days. Is there a chance you can wean off the neupogen early? It does keep my wbc up. but it I could even skip it for the last 2 wks, I would! Any ideas out there?

Did you get an injection of Neupogen? If so, that's not at all uncommon for people on TX to have to take that to keep their WBCs up.

to compare the effectiveness rate of sustained viral response (SVR) in patients with Pegylated Interferon dose modification and in patients treated by using granulocyte colony-stimulating factor G-CSF-filgrastim. (Neupogen). Study enrolled 47 patients with chronic active hepatitis C, aged 23-64. (38 male and 9 female). All patients had HCV genotype 1b. Significant neurtopenia (ANC<750 mm3) and severe neurtopenia (ANC<500 mm3) developed in 41 of 47 patients (87%).

I was on Neupogen from the 4th week of peg injection(48 wks) and I was instructed to do the Neupogen on Wednesday and Friday night was the Interferon. My 24 hour hotline nurse told me 48 hours to avoid interaction and the boost for WBCs 2 days before. It takes 24 hours to raise the WBCs and they peak at the 4-5 day which is the when the interferon lowers them. hope this helps. :) Many blessings, proud48.

Neupogen injection filgrastim

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