metolazone half life

i've just started taking metolazone to improve my breathing, i can hardly walk 1/2 block without having to stop. it seems that the breathing has gotten a bit better, but i've been hit with bouts of dizziness and fatigue hits me hard. i was wondering if anyone else out there is taking it and what type of reaction you may be having, good or bad.

I have a question regarding the diuretic Metolazone. As background, my father is quite elderly at 85, suffering for the last five years from congestive heart failure (CHF) following two heart attacks 10 years ago. His condition has been treated successfully to date by use of lasix diuretic.

Two weeks ago, he gained water weight, and lasix did not work. The doctor prescribed Metolazone, a more powerful diuretic. This removed water, but from about 2 days after he started Metolazone, he began a downward spiral. He developed a potassium shortage, treated by a supplement. Metolazone was stopped, but he has become too weak to walk, and his thoughts are clouded. His water weight is normal.

The half-life of a drug is how long it takes for half of it to be eliminated from the bloodstream. Hope that helps.

It has a very long half life, though I can't give you specifics. The dose and how long you were on it does factor in. Your doctor should be able to help you with your questions on this.

The GP contacted the heart failure Specialist who advised increasing spironolactone to 50 mg and if weight still increased he could take a metolazone every 2 nd day if necessary . Ihave worked out that if he has some salted peanuts small amount that the cramps are much reduced . But thank you both for your advice it is much appreciated.

They discharged his with O2 stats at 70 when walking and told me he had COPD. After being discharged for 2 hours he suffered another heart attack and was put on life support in ICU for 5 days, by some miracle he survived. They did that to him!!!! I could not prove medical malpractice becuase he has too many problems, but it did happen. So that happened in June and I decided to bring him home because I have no idea how long this will continue. Hes also legally blind and takes tons of meds.

decided to quit taking it on a monday felt fine all week untill sun when i went into serious withdrawl! so as far as half life im not sure? but you can bet i was back on it mon! so i guess it was in my system for 6 days after i stopped. p.s.

?? Does anyone know the Half life of SUBOXONE - Beprenorphine.? I HEARD it was 70 hours, but that's what I heard....unsure if that is even accurate?

whats the half life for syntriod. about how much time does it take to build up in you and also leave your system?

The mean half-life for multiple doses in the body is about 12 days, but very long-term kinetics are dominated by the kinetics of RBCs (half-life 40 days). RBCs store ribavirin for the lifetime of the cells, releasing it into the body's systems when old cells are degraded in the spleen.

ok plz if I am explaining this wrong (anyone feel free to correct me if I am ) The 36 hour half life mean half of the dosage is still active at 36 hours ??

I think heroin has a half life of 4-8 hrs, and methadown 20-36hrs, i understand that it takes 36hrs for half the drug dose to leave your body, but theres only 2 day deference between the two drugs but methadown takes months to kick and heroin weeks. thats the part i dont understand but theres only 2 day deference between the two. anyone with knowledge please try in a laymen terms to explain. thanks for any help in advance.

Then was given Cefuroxime, Linezolid antibiotic, corex syp and metolazone diuretics when partially conscious. He didnt eat much drank 50 ml water in last 14 hours and nothing after that. Later in the evening his oxygen was down to 70 SpO2. In 1.5 hours he was given oxygen with oxygen machine and the oxygen started to increase in a bit. In an hour heartrate started to fluctuate BP was almost NR. The patient suffered cardiac arrest few minutes later. The patient wasn't a major heart patient.

The half life of a chemical is the time it takes to break down become inactive. If the halflife is 10 hours then in 10 hours half the substance will be out of your system...in 10 more hours half of that..whick would be 25% would be left ..then in 10 more hrs 12.5 and so on . Hope it helps.

theres no half life after 5 days

there are people that live years and years with stage 4 COPD so just keep living. See the glass as half full and not half empty. Hang in there and get busy doing the things you like. Easier to say than do but honestly people are amazing and scores on tests just cannot tell you how long you have.

It depends on the half-life of the drug. One half-life means half of it is out of your systems, the second half-life means half of that half is out, and so on. It is generally accepted that after 7 half-lifes that a drug is entirely out.

I understand that the half-life of naproxen in the body is 12-17 hours. My question involves something I haven't found in other forums. When does it become safe to consume alcohol after taking an NSAID such as naproxen? If I take 1 unit of naproxen at 7:00 PM on Thursday, can I drink at 7:00 PM on Friday even though, according to the half-life, there is still about one-third the amount of naproxen in my system?

Hello Dezdon, I am glad you recognize you have some problems with oxy's. I don't know how you did it put according to my search you should be experiencing withdrawals. The usual elimination half-life of oxycodone following the administration of OxyContin was 4.5 hours compared to 3.2 hours for immediate-release. I found the following calculations on another wed site and compared it with other sites. This appears to accurate and in language that is understandable.

Metolazone half life

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