losartan marfan syndrome

ve recently had an echocardiogram that indicated that I had an dilatation of the aortic root. In investigating this online, I came across Marfan Syndrome. I appear to have a number of the symptoms of Marfan including the problem with the aorta noted above, as well as sleep apnea, an astigmatism in my eye, and early signs of emphysema (airtrapping indicated on a PFT test) at only 41 years of age.

We took him back for a check up and his cardiologist told us what my son has is rare and mainly seen in Marfan syndrome. His ascending aorta is a 2.9, at what point would surgery need to be done? He is 51 pounds. He also goes for a second opinion at Vanderbilt on May 12.

By the way, Pat, regardless of whether you have Marfan Syndrome or not, you might Google "losartan" and "Marfan Syndrome" to read articles on this topic. I don't think losartan is the best ARB, but it's the one being used in the current studies. All ARBs seem to work, some better than others. Efficacy is usually dose-dependent.

My 21-year old son was diagnosed with Marfan Syndrome at age 6. He has been on beta-blockers since that time. During his childhood and teen years, he had severe physical restrictions and had MVP as well as a dialated right ascending aorta. At this point in his life, the only symptom he sees an enlarge aortic root. It is enlarged at just under 4 cm. He has no joint pain. His breast bone is only slightly protruded. He does have sublixated lenses, but his vision is just fine with glasses.

Our son has Marfan Syndrome. A recent echocardiogram showed aortic annulus of 34 mm and a sinus of Valsalva of 48 mm, sinotubular junction 34 mm, and ascending 31 mm. Doctor said our son is near the threshold at which aortic root replacement should be considered. On various forums I've seen a 5.0 cm listed as a general number for aortic replacement. Of the measurements I listed from our son's test, which measurement is the one most often referred to in considering a threshold?

Hi ajr81, Be sure to talk to your cardiologist about the drugs called ARBs. Please visit www.marfanlife.net, even if you don't have Marfan Syndrome, and check the thread on "losartan.

Docs on here will continue to tell you about surgery and beta blockers, but will not (for some unknown reason that I'd love to hear) tell you about the latest developments in treating people on the Marfan/Loeys Dietz spectrum. I really get tired of typing this information out over and over, so I just tell people to click on my screen name and look at some older posts about angiotensin receptor blockers (ARBs) and ACE inhibitors.

I have some sort of connective tissue problem (not Marfan, but perhaps MASS syndrome), and I began using ARBs (valsartan) a few years ago, when this research first debuted. I graduated to a maximal dose (320mg/valsartan/day) about a year and a half ago. I don't know if this is wishful thinking or what, but my myopic progression and aortic dilatation both seem to have completely stopped (and aortic dilatation actually appears to be reversing to normal size).

There is some preliminary research into comparing atenolol versus losartan in the prevention of aortic root dilation in patients with Marfan syndrome through the Pediatric Heart Network (sponsored by the NIH). Though your son doesn’t have Marfan syndrome, there are some similarities in the aortic dilation that occurs between that and bicuspid aortic valve that may also respond to these medications.

I believe marijuana raises blood pressure significantly. Any raise in BP is bad for someone with an aneurysm. On a separate note, be sure you are informed about ARB therapy for Marfan patients. If you haven't heard of the research, google "losartan and Marfan." Aneurysms can be treated by pill in Marfan patients.

My 19 month old daughter has a pigeon chest, according to her doctor, and is very tall for her age. The doctor told me that she has Marfan syndrome and I was wondering if this is true. Could she have pigeon chest and not have Marfan syndrome? Thank you for your time and assistance with my question.

If not, then an echocardiogram with a measurement of the aorta is typically ordered as part of the evaluation for Marfan syndrome. There are very specific diagnostic criteria used to determine if someone has Marfan syndrome. It is not possible to determine your risk without an exam and a complete family history. At your appointment, the geneticist will take a detailed medical and family history.

So I have marfan syndrome which makes me a high risk mom. Here is a brief explanation of Marfan's syndrome since its not very common; it affects all the connective tissues in my body most importantly my blood vessels and more specifically my aorta. During childbirth my aorta is at risk of tearing which is potentially fatal and for the the birth of my first I had to vaginally deliver in the cardiac ICU in case they had to do surgery.

, do you mean that your nearsighedness is the only sign of Marfan Syndrome? In this case, you do not have Marfan Syndrome. First, do a web search for Marfan Syndrome (start with wikipedia) and educate yourself about that condition. Whether you have it or not is critical to any suggestions regarding your vision. Second, -6 myopia is only moderate myopia. People with Marfan Syndrome usually have extremely high prescriptions, often with high astigmatism. So this doesn't fit either.

Marfan syndrome is a genetic condition that affects the connective tissue in the human body. Connective tissues are proteins that support skin, bones, blood vessels and other organs. Marfan syndrome symptoms can be mild to severe. The symptoms vary widely in severity, timing of onset, and rate of progression. Marfan syndrome is inherited in an autosomal dominant manner, which means that having a single mutation in the FBN1 gene is sufficient to cause the condition.

Hi Sue, Please take a moment to click on my screen name to view my many prior posts on this topic. Also visit www. marfanlife .net/bb3 (remove the spaces; I put them in there so that this website would let me display the address) and look at the "Pharmacy" section for extensive discussion on this topic. My understanding is that it would be OK for a teenager to be on this type of drug, especially one who is only 3 years from being an adult.

He has many of the features of marfan syndrome, which is why we had his echo. We are soon to see a cardiologist who specializes in cardiovascular mri's. What questions should we ask this specialist and what could cause such symptoms in someone as young as my son?

, 125 lbs and otherwise healthy except for a solitary (healthy) kidney and peanut allergy. I am taking him to see a geneticist at the end of the month to rule out Marfan Syndrome. The only other Marfan characteristics he presents with is myopia and his height. His cardiologist is going to do a repeat echo in 6 months. What else should we be doing? Betablockers? What is the prognosis for aortic root dilation? He is an athletic and social child. He plays baseball on a travel team.

poor eye sight his waiting on genetic testing for marfan syndrome he has started on losartan tablets .....

I'm 33 and female, and I went to the doctor because my sister and dad have hypertrophic cardiomyopathy. I was screened at 20 and didn't have it, but didn't realize that I needed to get screened every 5 years. The doctor noted that I was tall and thin and asked if my sister looks like me, and I said yes. He said that I may have Marfan Syndrome. He asked me to do two hand tests, which didn't qualify me for Marfan.

My 10 yr old son has just recently diagnosed with Marfan Syndrome. His aeortic ventrical is enlarged mild to moderate and the right side of his heart is considerably bigger than the left. His doctor has referred to it as enlarged. He has a resting heart rate of about 108. I was told that the right side of the heart being much bigger than the left is a different disorder than Marfan. What is the name for it?

Hi, How are you? Marfan syndrome is a disorder of connective tissue which can affect the skeletal system, cardiovascular system, eyes, and skin. It is caused by defects in a gene called fibrillin-1 which is the building block for elastic tissue in the body. In most cases, Marfan syndrome is inherited but up to 30% of cases have no family history. Check with your doctor for proper evaluation. Regular prenatal consult is important. Take care and do keep us posted.

So with absolutely no family history, me being normal height (probably a little below average) and weight for my age, normal arm span compared to height, no pectus excavatum, no stretch marks, no dislocated lens, or any other physical characteristics besides the high arch palate and possible positive thumb/wrist signs, it doesn't seem like I meet the criteria for Marfan Syndrome on the National Marfan Syndrome website. There is still a possibility that I can have it?

Have you ever heard of Marfan Syndrome? If not, you might look at a private message from me to see if you have symptoms that would prompt you to ask a doctor about it.

Losartan marfan syndrome

Common Questions and Answers about Losartan marfan syndrome

cozaar