Hi everyone, I have take a PEP treatment for 25 days, which included Lopinavir&Ritrnonavir & Truvada.
I have had diarrhea, anxiety, sleepless nights, depression, numbness in hands and legs, while using these
medications. Its been a week i stopped the medication and all my HIV tests have been negative so far.
Has anyone read the news that came out yesterday about hpv treatment with the Lopinavir drug?
It shows some promising results so I'd like to get anyone's take on this.
This study has to do with an HIV retroviral medication, if used on HPV patients, it might cure them. The drug is already produced, called lopinavir, however we need to make a topical version that is more potent:
http://bodywart.com/hpv-news/lopinavir-destroy-hpv-infected-cells/
You might also want to look into a antiviral drug recently produced by MIT called DRACO. It sounds very promising but needs to be tested on actual humans.
1 - would PEP be effective even if the source has a high viral load?
2 - After the 28 days, can I drink alcohol?
Thank you very much in advance, I am quite distressed about it.
Zidovudine and Lamivudine Tablets ,Lopinavir/RitonavirOral Solution .i want to know ,will it work?how much percent will i avoid being infected?thank you all!
So, I am at the 15th day of my pep regime and have been strictly adhering to the program till today. I have been taking lopinavir ritonavir along with tenofovir. I am taking 2pills twice for the first one and one pill once a day for tenofovir. Today my bottle of rito/lopi finished after I took my first dose. I went to the doc clinic which was closed and he says i can only get the meds tomorrow.
11,12am), I take hiv block drugs from doctor, these drugs are Tenofovir Disoproxil Fumarate Tablets , Aluvia (Lopinavir and Ritonavir Tablets) and Lamivudine Tablets. I have take these drugs for 28 days (until 2013.10.8),at 2013.10.9(1 day after taking drugs) , I have take a HIV Duo or Combo (4th generation) test and the result is negative .
so, I want to know
1. Could these drugs delay the hiv window period , so that the combo tese was not correct?
2.
1-My partner tested Negative(Antigen/ Antibody) on 22 days post exposure
2-Thinking that i might be developing facial Lipodystrophy (slight facial fat loss under cheek bones). I cant tell if my face was like this before the treatment or it is just an illusion.
What can i do to really know if i developed some lipodystrophy ? any test u can advise about?
Methadone has a slow metabolism and very high fat solubility, making it longer lasting than morphine-based drugs. Methadone has a typical elimination half-life of 15 to 60 hours with an average of i would say about 22. However, metabolism rates vary greatly between individuals, up to a factor of 100 ranging from as few as 4 hours to as many as 130 hours, or even 190 hours. So it's hard to say.
The water solubility of bilirubin allows the bilirubin to be excreted into bile. (Bile then is used to digest fats.)
Total bilirubin, if I remember correctly, is the conjugated hemoglobin, since there is also another portion that is not conjugated.
What the elevated total bilirubin means at this point is 'something' is going on, but you may need more information before your doc can determine the cause.
This is known. Are there any similar action in the protease inhibitor, such as Kaletra (lopinavir) for example?
Have you ever thought about that?
I read - sometimes laugh. Simvastatin, vitamin D, which the Chinese poeben, mythical new drugs, masturbation with measurements of the level of HBsAg, and other nonsense....
The main requirements for them are (1) high IFN-inducing activity, (2) absence of side effects, (3) wide spectrum of antimicrobial activity, (4) broad therapeutic security and, (5) good solubility in water and biologic liquids. IFN inducers stimulate IFN production in different cells and organs, and that determines the strategy for their application. Amixin (OOO "Lancepharm," Moscow, Russia) induces IFN-?/? production mostly in T cells. Cycloferon (NTFF "Polysan," St.
However, factors that can affect absorption include oral pH, salivary enzymes, lipid solubility, and molecular weight (molecules may be too large to pass through the mucous membranes). A sublingual product, specifically created to ensure effective absorption, is recommended.
What is my overall risk of acquiring HIV, taking in consideration all that I have described above?.
Thank you very much in advance.
A 12 years old girl had a blood transfusion with hiv blood, she took PEP( tenofovir, emtricitabine, ritonavir-boosted darunavir (subsequently changed to lopinavir) and raltegravir) after 24 hours and had these PEP for three months. This girl also has cssr5 dna which is a dna that hard to infect hiv. After 8 months, she had a negative result on HIV RNA and HIV ag/ab test. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226216/).
(By the way, although losartan is currently being researched in Johns Hopkins clinical trials, other ARBs such as telmisartan are probably most effective given their increased lipid solubility and thus increased tissue penetration.)
I strongly encourage you to visit www.marfanlife.net and find the very lengthy thread titled "Losartan" or something to that effect. Probably some of the most important reading of your life.
the brain is affected quickly as alcohol will cross what is called the blood-brain barrier due to its solubility. this can compromise involuntary actions such as heartbeat, breathing and gag reflex. organs such as the liver and pancreas can suffer tissue destruction resulting in everything from lowered function and scarring to complete organ failure. for diagnosing existing damage, your doctor can order bloodwork including a liver panel to check things like enzyme levels.
Insulin glargine is a human insulin analog that has been designed to have low aqueous solubility at neutral pH. At pH 4, as in the LANTUS injection solution, it is completely soluble. After injection into the subcutaneous tissue, the acidic solution is neutralized, leading to formation of microprecipitates from which small amounts of insulin glargine are slowly released, resulting in a relatively constant concentration/time profile over 24 hours with no pronounced peak.
Treatment with PEG-IFN-alpha 2a, 180 ug/week and ribavirin 1000 mg/day was started, and lopinavir/r/3TC/tenofovir was continued. HCV RNA was cleared after 12 weeks and AST levels normalised. At month 13, still on PEG-IFN/ribavirin therapy, AST levels increased and HCV RNA became detectable. Genotyping showed HCV genotype-2. The patient admitted he had participated in one more ‘fist-@%* king’ party at month 11 in Berlin. The patient denied IVDU at any time.
Hi & Welcome!
A BB King fan, eh? Well, Congratulations on your 3 Days off Subs! While the majority of people I've known (including myself) to come off Bupe experience w/d's b/w 24 & 48 hours , some have reported that it 'ramps up'/intensifies between 72 - 96 hrs. Have you had any kind of opiate habit before? If not, it's just possible that you might experience milder w/d's than someone w/ a longer history.
For those too concerned about catching HPV(which most will do anyway), there's great news about the use of the lopinavir drug to cure HPV. What do you think, Dr. Handsfield?
Sorry again Teak Lamavudine (Lamavir) Stavudine (Stavir) and Kaletra
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