Hi everyone, I have take a PEP treatment for 25 days, which included Lopinavir&Ritrnonavir & Truvada.
I have had diarrhea, anxiety, sleepless nights, depression, numbness in hands and legs, while using these
medications. Its been a week i stopped the medication and all my HIV tests have been negative so far.
Has anyone read the news that came out yesterday about hpv treatment with the Lopinavir drug?
It shows some promising results so I'd like to get anyone's take on this.
Atorvastatin is supposed to be one of the two most effective statins in lowing cholesterol so you are on a good one. Bioavailability is how well a med is absorbed and used by the body and bioavailability varies among the statins. It's actually a desired thing. The liver is the target organ so if it is slowed down in the liver (where this happens), it's in the target organ. But honestly, that is hard for me to understand.
This study has to do with an HIV retroviral medication, if used on HPV patients, it might cure them. The drug is already produced, called lopinavir, however we need to make a topical version that is more potent:
http://bodywart.com/hpv-news/lopinavir-destroy-hpv-infected-cells/
You might also want to look into a antiviral drug recently produced by MIT called DRACO. It sounds very promising but needs to be tested on actual humans.
1 - would PEP be effective even if the source has a high viral load?
2 - After the 28 days, can I drink alcohol?
Thank you very much in advance, I am quite distressed about it.
Zidovudine and Lamivudine Tablets ,Lopinavir/RitonavirOral Solution .i want to know ,will it work?how much percent will i avoid being infected?thank you all!
So, I am at the 15th day of my pep regime and have been strictly adhering to the program till today. I have been taking lopinavir ritonavir along with tenofovir. I am taking 2pills twice for the first one and one pill once a day for tenofovir. Today my bottle of rito/lopi finished after I took my first dose. I went to the doc clinic which was closed and he says i can only get the meds tomorrow.
Although a standard meal did not affect ribavirin bioavailability (F1), administration of ribavirin with a high-fat meal increased bioavailability by 46% relative to the fasting state. A high-fat meal prolonged the duration of the zero-order input part of the absorption model, with D1 increasing from 0.498 h (fasting and standard meal) to 0.740 h. The type of meal also influenced the first-order input part of the absorption model (Table 1).
11,12am), I take hiv block drugs from doctor, these drugs are Tenofovir Disoproxil Fumarate Tablets , Aluvia (Lopinavir and Ritonavir Tablets) and Lamivudine Tablets. I have take these drugs for 28 days (until 2013.10.8),at 2013.10.9(1 day after taking drugs) , I have take a HIV Duo or Combo (4th generation) test and the result is negative .
so, I want to know
1. Could these drugs delay the hiv window period , so that the combo tese was not correct?
2.
1-My partner tested Negative(Antigen/ Antibody) on 22 days post exposure
2-Thinking that i might be developing facial Lipodystrophy (slight facial fat loss under cheek bones). I cant tell if my face was like this before the treatment or it is just an illusion.
What can i do to really know if i developed some lipodystrophy ? any test u can advise about?
When a medication is administered intravenously, its bioavailability is 100%. However, when a medication is administered orally, its bioavailability decreases because not all of it is absorbed. So 70% bioavailability means that, from the dose you took, 70% of it reached systemic circulation.
"Two studies have been carried out to assess the effect of food (ie, a high-fat breakfast) on the bioavailability of a SINGLE oral dose of ribavirin. An initial study by ICN Pharmaceuticals, Inc.
Also as a side note, Opana oral bioavailability is actually very low. Lower than morphine I believe the bioavailability is around 10 percent. However, if you reach your optimal dose, bioavailability matters little.
I see that this post is from October 2011. But since I have this typed, I'll post anyway :) Good luck and gentle hugs.
This is known. Are there any similar action in the protease inhibitor, such as Kaletra (lopinavir) for example?
Have you ever thought about that?
I read - sometimes laugh. Simvastatin, vitamin D, which the Chinese poeben, mythical new drugs, masturbation with measurements of the level of HBsAg, and other nonsense....
Blood tests are not accurate for testing the active bioavailability of sex hormones in the cells and tissues. They only test what's in the blood stream. They aren't accurate for testing when a patient is using bioidentical topical creams. I've had two holistic doctors tell me this and have read numerous articles about which testing is correct depending on which type of hormones you're taking.
The ascorbate in Ferrous Ascorbate helps retardation or prevention of Fe(II) oxidation by ascorbate and to the existence of Fe(II) as a chelate with ascorbate ( vitamin C if you like ). Ferrous Ascrorbate will have a better bioavailability but you can add a vitamin C and vitamins B complex with sodium feredetate and have pretty good results.
Depending on your needs; are you lacking iron? anemia?
What is my overall risk of acquiring HIV, taking in consideration all that I have described above?.
Thank you very much in advance.
The component of the final population pharmacokinetic model that describes the absorption phase is complex. Although a standard meal did not affect ribavirin bioavailability (F1), administration of ribavirin with a high-fat meal increased bioavailability by 46% relative to the fasting state. A high-fat meal prolonged the duration of the zero-order input part of the absorption model, with D1 increasing from 0.498 h (fasting and standard meal) to 0.740 h.
Thank you for your question,
Yes, it is recommended you take it in the morning on an empty stomach, at least 30 minutes before food. Taking levothyroxine with food may cause reduced bioavailability and may lower drug levels leading to signs or symptoms of hypothyroidism. In addition, cottonseed meal, walnuts, and dietary fiber may decrease absorption of levothyroxine from the GI tract.
Often I’ve had twitching in various parts of my body, even my eyelid, and after taking a magnesium supplement (Magnesium citrate is one of the best and has very good bioavailability; Magnesium Oxide is not recommended because of its very poor bioavailability!), my twitches stopped within a day! It’s easy to find on Amazon. I only mention these things because it is common to have low Vitamin D as well as low Magnesium. I hope your husband is feeling better soon.
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