Like Jerzeegal, I have opted not to take the beta-blockers
for PVCs. I get over 20,000pvcs per day, but I have tried Toperal, Inderal, and the last one was Atenolol.
Both the Toperal and Atenolol (one half a 25mg tablet), put me on my butt. They made me feel like I was walking under water with one of those old fashioned dive suits, you know with the big helmut. lol.
None of the beta-blockers have touched the frequency of the pvcs, but I had the fewest side-effects with the inderal.