Duration of action is different for different insulins. We have rapid acting; older insulin Humalin-N has an onset of 15 - 30 minutes compared to the modern insulins such as Aspart (novorapid for me) and Humalog, which have an onset of about 10 - 15 minutes.
Moderate acting insulins are the ones we use for basal (background) insulin. Examples are Humalin-R (older insulin), levemir, lantus etc.
Then we have the action profile: whether there is a peak or not.
Levemir is a basle insulin, meaning it works for 24 hours. Like a background insulin. the amount of Levemir taken has nothing to do with the amount of carbohydrates (carbs) you eat. That type of insulin is called a bolis insulin, like Apedra, Novalog... that insulin is taken according to how many carbs are eating and YOUR particular carb to insulin ratio.
It was working well for a year. Then blood was becoming high, Doctor gave me LEVEMIR. If I take 10 units of humalog, after two hours sugar drops 4 points, I think this is the right dose for humalog for what I eat. I eat 60 gram Carb every meal. But 3 hours, sugar tries to go low, but insead, it bounces back and proceede to values and I start to feel hypo, though I never see sugar 9. It is not hypo value, why sugar bounces up, why feel shaky, fear etc. I use LEVIMIR as base insulin.
I am not physically restricted - I walk 1 mile or more day and do 10 minutes of other light exercises most days. My BP runs under 120/80 most of the time. I understand carvedilol helps prevent stiffening of the heart muscle and can help restore LV function to some degree. How specially, so it do this? What is the biochemical mechanism?
If you believe your are reacting badly to Lantus (or any other medications) you should ask your physician for an alternative, at least to verify it is the medication and not some other factor that is causing the problem. Lantus is popular for it's 24 hour action, but so is Levemir (Novo Nordisk). NPH insulin can also be used for long acting insulin, though two injections may be needed to get the 24 hour coverage.
The Levemir is NOT on a sliding scale. It is a given does once a day Or twice a day. 12 hours apart.
is his 224 after eating or first thing in the morning before food or drink?
It was just unreliable in that it would sometimes leak with injection so I never knew if I was getting the proper dosage. I switched to Levemir (flex pen) a couple of years ago, and it has been fine. Both Lantus and Levemir are the peakless insulins. They provide your "background coverage" all day long (24 hours). When you eat, you need the fast acting insulin like Novolog to act quickly to cover the meal. For some, Lantus and Levemir act the same.
The mechanism of action of Campral® (acamprosate calcium) Delayed-Release Tablets in maintenance of alcohol abstinence is not completely understood. Originally, several neurotransmitter systems, including GABA, were investigated for a possible role in Campral's mechanism of action. However, recent evidence suggests Campral's main interaction is with the glutamate system. Chronic alcohol exposure is hypothesized to alter the normal balance between neuronal excitation and inhibition.
http://www.nasdaq.
Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.
However, you may find that your fasting blood sugar becomes higher due to the dawn rise now being at the end of the lantus action. Alternatively, talk to you dr about using levemir. This is dosed morning and night and the dose can be different for morning and evening to target optimal blood sugars. There is also a new insulin called Tresiba. Many find that this gives very stable blood sugars with less risk of lows. You may also discuss this with your Dr.
I am an insulin dependant diabetic. I was out of Levemir for several days and I tried to control with Novolog. Wednesday and Thursday I was running over 600. Yesterday I got my Levemir and started taking it right away. It took most of the day to get down to 350. I was feeling real sick all day. Sleepy, dizzy, nauseous. muscle weakness. I slept from 6:00 pm until 10:00 am. My numbers were up to 500 again. I got them back to 300 by 3:00 pm, but have continued to feel just as sick.
HIV is transmitted by;
Unprotected penetrative anal and/or vaginal sex
Sharing works with other IV drug users
Mother to child
You never had an exposure.
Shortness of breath is called Dyspnea. A Google search returned this page showing Victoza causing Dyspnea.
http://www.ehealthme.com/ds/victoza/dyspnea
And, this report
http://www.druginformer.com/search/side_effect_details/victoza/dyspnea.
Potassium is a chemical element and it is part of the electrolyte that should be in balance with other lytes to adequately conduct an electrical impulse that originates with the sinus node in the right atrium. The mechanism of action is not completely understood, but what is when a voltage (unit of potential for conduction) and electrolyte there will conduction and passage of electrical impluses.
Are you saying stress has impacted your weight and that is impacting your diabetes? I'm under a lot of stress currently too and am eating myself out of house and home. Sigh. Stress eating is real. My goal is to work on the stress as well as my health. Well, they are tied together, so . . . anyway, I'm sorry that you have 'one more thing'. You wrote this end of October. How is it going now?
http://www.medscape.com/viewarticle/578705
Ribavirin improves early responses to peginterferon through improved interferon signaling.
Gastroenterology. 2010 Jul;139
The therapeutic mechanisms of ribavirin for hepatitis C are unclear. Microarray analyses have shown that ribavirin increases induction of interferon-stimulated genes. We evaluated viral kinetics, serum cytokine expression, and viral mutagenesis during early stages of peginterferon therapy with and without ribavirin.
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