you are in the US, and you still have doctors prescribing lamivudine to you! I mention this first because these days, I find that in most cases, doctors prescribing it should be immediately be put under probation! Yes... I have seen these warnings about use of lamivudine by breast-feeding mothers. More importantly, lamivudine is one of the earliest drugs for Hep B, and the one that Hep B viruses adapt to most easily.
tenofovir, no resistance
entecavir, 1,5% resistance but cannot be used on those using lamivudine because in this case resistance can go higher than 50%
interferon
if i had a doctor prescribing me such rubbish useless toxic.....i d destroy his life....
run away from the doctor that is prescribing you lamivudine.
Before biopsy ultrasound was normal. Fibrosis was found 3/6 prescribed lamivudine since 2013.We dont have fibroscan in our city. the treatment was good my alt ast decreased to normal levels.But in June 2015 there was some problem with the ultrasound. It said slightly coarsened parenchyma. The other details was fine. Last month another ultrasound was done. This time slightly heterogenous parenchyma possibly secondary to hepatitis b. The other details were fine again.
1. I am HBV carrier, and I am also under treatment with taking lamivudine 100mg daily. Will this impact the result? Will lamivudine/HBV virus cause false negative?
2. Because I am taking lamivudine daily, will this cause the delay of seroconversion. I think the test was done about 18 months after events that I thought maybe risky.
3. My test is Combo TypeI/II antibody and p24 antigen QUAL CMIA. Is it reliable?
4. My HBV DNA level is sometimes undetectable, but sometime a few hundreds.
well my baseline hep b viral load was 11000 iu/ ml, I took lamivudine + hepantivir daily for three months and the viral load was 159 iu/ ml. I stopped taking hepantivir and continue with only lamivudine when at that time it came to undetected. there wasn't much information about hepantivir I have to burn the remaining two packets of it.
stop lamivudine immediately or switch to tenofovir, it is decades now lamivudine is not used because it can lead to cytopatic hbv mutations that cannot be control with any medication leading to cancer and cirrhosis despite hbsag negative, hbvdna undetectable and normal ast-alt, another reason not to use lamivudine is that it is even totally useless on hbv
the hbsag of the virus mutates to a form where the virus destroy cells directly even without replication
hbv cure is achieved only by sequen
Without taking any drugs, viral load was 22,000 in september 2009. 46,000 in december 2009. Doctor recommended lamivudine in January. Took lamivudine and by June 2010, viral load was undetected. have read in many forums that lam is not the best, approached my doctor with this concern and she sugessted tenofovir. Should i start tenofovir immediately, how should i start. Should i just abruptly stop lam and move on to tenofovir, should i use both and gradually stop lam after a few day/weeks.
most of the doctors practicing here are even not aware about this drug. I ve seen a lot a physicians still prescribing lamivudine then what better can u expect from them.
Hepatic decompensation was not prevented by lamivudine compared to placebo or entecavir compared to lamivudine in three underpowered trials.
Hepatocellular carcinoma was not prevented in four studies with inadequate size and duration. In one RCT, analysis that adjusted for country, sex, baseline ALT level, Child-Pugh score, and Ishak fibrosis score and excluded five individuals who developed HCC within the first year of the study found a borderline significant effect of lamivudine.
Little is known about whether the antiviral agent entecavir is more effective than a less potent drug, lamivudine, in reducing the risk of death and hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB).
Methods
We performed a retrospective analysis of data from 5374 consecutive adult patients with CHB, treated with entecavir (n=2000) or lamivudine (n=3374) at a tertiary referral hospital in Seoul, Korea from November 1, 1999 through December 31, 2011.
10.300 copies/ml . I got lamivudine 100 mg /day vitamine E 4oo ui /day, orange juice everyday 50 cc/day ,and others fruits,2 months later my blood test showed DNA/HBV/PCR negative (<200 copies ),checked regularly every 3 months untill now still negative level. SGPT 75- 90 ui/ml constantly,never down a normal range,since 2008 March untill now. HBsAg negative level ,HBsAb negative level ,others test are normal levels .Is i got recovery from Hepatitis B ?
I have tested positive to Hbsag for more than a year now. I was placed on lamivudine, methionine and essential forte. d doctor never ask me to do viral load test anytime I see him he do ask me to do LFT and subject me to d early medications I listed. so a friend advice me to go teaching hospital were I can see a specialist. my question here is now that I have been on medication for a year without knowing my viral load what is d implication ?
I have Hep B positive for 15 yrs (since 1997). Was treated with Lamivudine ( Nov 2009 to Nov 2010). Feb 2012 test results shows HBV DNA 29426 copies/ml, ALT 54 U/L, Anti-HBe positive ( Competitive ELISA, Sample OD 0.116, cut-off OD 0.701), HBe AG Negetive, Fibroscan- CS(KPa) 1.7, IQR(KPa) 0.5.
Do I need medication right now. I got a Liver doctor appointment in April 2013. Can I wait till April or I should find other way of treatment?
BACKGROUND: Nucleoside analogues such as lamivudine for chronic hepatitis B have an excellent safety profile while patients are on therapy but reactivation flares occur in 19-50% of patients after stopping therapy, some of whom develop liver decompensation. AIMS: To describe and report three cases who developed fatal hepatitis B reactivation after stopping nucleoside analogue therapy.
I am a 26 year old male having hbsag and hbeag=+ve,hbv dna =1070 iu/ml(Taqman) but my LFT results are normal(sgpt=37,sgot=33).My doctor has asked me to take lamivudine 100 mg for 6 months or until hbv dna becomes -ve.My mom is taking lamivudine for the last 7 months after her hbv dna crossed 8 lacs iu/ml.Probably I have been infected from my birth.Is it possible for both of us to completely cure Hep. B after taking lamivudine.
28
I am Hep B carrier under lamivudine treatment. Last HBVDNA test was last year Aug and negative. HBeAg changed from positive to negative after 3 years of lamivudine treatment and has kept as negative so far. However, my doctor want me to continue take lamivudine after sero-conversion. Moreover, happened to test ALT (part of yearly body check) 4 days ago before above test, and the value is 42. So far, I am feeling great, eating and sleeping normal (apart from anxiety).
I got infected with HBV 11 years ago. Right now I eat Tenofovir and Lamivudine everyday. I used to take thymomodulin - A good medicine to strengthen your immune system.
HBV-DNA PRC: Negative.
I am a 26 year old male having hbsag and hbeag=+ve,hbv dna =1070 iu/ml(Taqman) but my LFT results are normal(sgpt=37,sgot=33).My doctor has asked me to take lamivudine 100 mg for 6 months or until it becomes -ve.My mom is taking lamivudine for the last 7 months after her hbv dna crossed 8 lacs iu/ml.Probably I have been infected from my birth.Is it possible for both of us to completely cure Hep. B after taking lamivudine.
I was examined by my first doctor and advice me that I am not qualified for medication but my employment requires to pass this Hepa B case so I look for another doctor that could give me something for medication.. The doctor and give me Lamivudine(Zeffix)..
My question is; Is there someone in this forum that had experience with this level of UI/ml that been cured and how long?.. My employeer is waiting for my respond but I cant give them exact or approximate date when will cured..
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