m currently taking Kaletra and Combivir.
Really I do not get why doc did not gave me the full drug combination, Combivir+Kaletra, at the intial 10 hour mark. Now I‘m wondering whether this whole PEP thing still makes sense.
Do you have any experience with the efficacy of Combivir alone, or whether adding another drug later, a PI like Kaletra, may still have erficacy in preventing infection?
Apologies,just needed to share this.. could you advise?
Is combivir an appropriate HIV nPEP regimen for one time unprotected encounter with CSW of unknown status in Kenya? I'm a 24 yr male from UK. Insertive vaginal and oral. Asked about Kaletra and doc said it's low risk doesn't recommend, but I am still very worried. Started within 12 hours, but still within 72 if kaletra should be added. I feel terrible of course but appreciate any advice.
3 days later my doctor switched me from Sustiva/Combivir to Kaletra/Combivir. A few days after that I began to develop a mild sore throat and a quarter size rash on my penis. On July 24th I got a Stat-Pak HIV test at a clinic which came back negative. By July 30th, 2008 (maybe a few days earlier) I developed a small quarter size rash on my right foot but this rash was nothing at all like the rash on my penis a few weeks earlier.
Again i have started PeP after 28 hours . This time using both Combivir and Kaletra. After the first dose i experienced rather severe diareha and some mild acid taste and abdomen pain.
So i have a lot of questions regarding the oportunity of PeP in both cases. I am a bit worried about the short term side effects and long term side effects. Should i continue PeP with both drugs? Will they damage my liver etc . Looot of questions :)
Thank you in advance and excuse my poor english.
P.S.
if I have a PCR RNA viral load test done 1 week after exposure, what can I expect from the reliability of the results? If I get a negative is it actually the cases that I very likely did not contract the virus or might the retrovirals just suppress the viral load to an undetectable level?
Four months ago i had a condom break on me on a girl with her period that had unknown status and dr put me on Combivir with Kaletra, and i stopped after 10 days when the girl showed me her test result. I did a test 1 month ago and i was negative, and now i am in the same spot. I already started on the Combivir every 12 hours and the kaletra every 12 hours i have left...
Please Dr, what are my chances of risk??? I do not want to take PEPs if not necesary..
I went 30 hrs after my exposure to the hospital and they gave me PEP (1 combivir and 2 kaletra twice per day) coming back to my country after 3 days i forgot the pills that i bought in switzerland and the doctor here suggested i take 1 atripla pill instead every night !!!
do you think this is feasible ( what is your assessment to the situation?!
Again i have started PeP after 28 hours . This time using both Combivir and Kaletra. After the first dose i experienced rather severe diareha and some mild acid taste and abdomen pain.
So i have a lot of questions regarding the oportunity of PeP in both cases. I am a bit worried about the short term side effects and long term side effects. Should i continue PeP with both drugs? Will they damage my liver etc . Looot of questions :)
Thank you in advance and excuse my poor english.
Please help me!
Here I have few concern of my own experience. I was put on PEP (Kaletra & Combivir) 68 hours later after protected vaginal sex and unprotected oral sex (the CSW gave me bj).
I got rash on day 8 of my PEP accompany with mouth ulcer and white tongue.
My test on week 6 is negative. And on week 9 I got another negative test called Combo Test.
Unfortunately, the same kind of rash appear again on week 11 with same mouth ulcer and white tongue.
rash on the foot,shortness of breath,sore throat,sore arm pits, malasie, bad headaches, fatigue, constipation, and diarrhea
after 42 days i was taken off the PEPs (kaletra and combivir) and almost immediatly the sore throat was reduced and the headaches have gotten slightly better. however my arm pits are still sore.
i tested negative at 7 days and 30 days.
In the morning of Thursday I took 1 Kaletra. In the evening of Thursday I realized I misread the label and took 2 Kaletra though I forgot to take the Truvada because I was used to taking the other medicine in the morning (I’ve also not been thinking straight and been very stressed, I made a mistake). On Friday morning I came to my senses and took 2 Kaletra and 1 Truvada and set a plan so I wouldn’t mess it up and that’s the regiment I will stick too.
Hi Teak, i went to the university hospital in switzerland and the doctor said that despite the low risk its better i go for PEP .. he gave me combivir and kaletra ... only i want to say that despite my decision to take PEP and i hope i will be able to handle it ... your answer gives me peace that there is almost no chance i get hiv from oral sex ...
But as I was not sure of this I decided to take pep, which was at first combivir and kaletra for 2 days, afterwards combivir only. I adhered toi the regime in 100%. I recently tested with hiv duo test 30 days after completing pep and the result was negative. As I am not from UK we have a different testing schedule (i suppose the old uk-one with 6 weeks, 3 and 6 months). But can I consider my 4 weeks post pep reliable?
Also there was some inconsistency in terms of which medicines I was taking. Day 1-4 combivir with kaletra, day 5-6 only combivir and day 7-10 combivir with tenofovir. So far I've been taking pep for 10 days so far and the side effects are really bad especially nausea. It's been really rough time and I feel like I can't handle the medicine anymore..feel really sick from it.
Hi, appreciated . Anyway went to doc today and be said no harm getting on PEP so I've just started my dose of combivir and kaletra. 4 pills twice a day.
My partner claimed that he is negative yet I know that he had few partners before me. I talked with HIV specialist and he put me on PEP (combivir+Kaletra) for 28 days which I started at ~65 hours. My adherence to the regime is extremely strict. In addition to the usual digestive side effects, I did not experience any other problem until last week. At 1.5 week mark I started to have a throat discomfort which is still around (more like a post nasal drip rather than sore throat) and stiff neck.
RN,
I was stuck by a tbs syringe after giving heparin sq. After finding out that he was + hiv. I started prophylaxis combivir/kaletra 5 hrs after the incident.There was no blood in the syringe. I let it bleed and washed it with soap/water. What are the odds that I can convert to hiv+.
I am also worried about the possible side effects of the drugs. I am planning to discontinue the drugs-...I feel tired easily and has a history of high cholesterol/triglycerides.
Hello I ran into an incident last night and ended up having unprotected sexual intercourse with a stipper. I started the first dose of Combivir last night and was wondering if the side effects get too bad and I cannot take it for the full 28 days, what I should do. They cannot get any other PEP prophylaxis treatments besides the Combivir and was really worried about the side effects of this medication, as I am already feeling nauseated.
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