As you well know Humira is an immuno-suppressive
drug , which mainly inhibits TNF (tumor necrosis factor).
There's a growing amount of evidence of the development of Autoimmune conditions, related to TNF inhibitors, such as Remicade, Humira and other biologics.
I took my first Humira shot in my leg on Monday and last night my leg began to hurt really bad. It is a pain that is hard to describe. I told my husband it was a "bone pain" it hurts down deep in the bone from my knee to my hip joint. Today it is hurting mostly in my hip joint.I take darvocet daily for pain and it really isn't helping and neither is naproxen. Is this normal after the first few days of the injection?
Is it possible that you are having muscle pain, not joint pain? This could be fibromyalgia. I thought I had RA also, but I did not test positive for any of the markers, even the sed rate. There was no inflammation, that's why the anti-inflammatories don't work. Could you have osteoarthritis in your knees? I have that.
Just a thought. I haven't had too much relief from FM anyway, but just thought to mention it to you.
But the joint stiffness and crepidess is still there and i get break through pain even though i still take 600-1000 mgs of ibuprofen a day. I was given percocets and vicodin to take for the break thru pain, but they are poison, addicting and i was developing a very high tolerance to the drugs, which scared me straight into not taking them anymore. My question is this, i have never been really diagnosed with anything other than, "we really don't know".
t really have issues with small joints although one joint in my fingers do hurt (same joint in both hands), it's mostly my hips, back, shoulders and ankles and knees but not very often with the knees and nothing compared to the others. I've also been getting swollen glands in my neck but my throat feels fine and I can chew and talk but can't turn my head without it hurting.
Unfortunately, yes, these are side effects of humira. Cold and flu symptoms are listed as common. From drugs.com: Common side effects of Humira include: upper respiratory tract infection, headache, injection site reaction, skin rash, antibody development, sinusitis, and pain at injection site. Other side effects include: urinary tract infection, abdominal pain, and flu-like symptoms. https://www.drugs.com/sfx/humira-side-effects.html I'd tell your doctor you are experiencing this.
I have been treated for rheumatoid arthritis with Humira for 7 months including a combination of Humira and methotrexate for the past 2 months. I also take 5mg of prednisone, and 6 Azulfadine tablets each day. I was taking Humira once every fourteen days and I am on 15mg of methotrexate a week. About a month ago, I started experiencing numbness in my toes and feet. I mentioned it to my rheumatologist but she wasn't concerned and simply told me it wasn't rheumatoid arthritis.
Doctors do not seem to have answers for what we confirm mystery illnesses, but I really want to pass on to you some information that you can read for yourself and keep in mind that knowledge is power. A book published November 2015 it is a must-read for people like yourself and I with joint pain mystery illnesses such as fibromyalgia and the like. The name of the book is called the medical intuitive. The author is Anthony Williams.
Hi monicaroni, I have been taking Humira almost 8 months. I take humira for Crohns Althougth reap the benefit for the AS. I am thinking that you probably had a concurrent infection brewing when you Started Humira. Good Luck managing your AS, I appreciate how difficult it can be with mobility issues, and treating pain.
This is because any immune mediated disease like Crohn’s produces excess of an inflammatory protein called TNF-alpha, which causes cellular damage along with pain and inflammation. Humira blocks the action of TNF. Thus once the cellular damage heals, and the inflammation subsides, the diarrhea will subside and the digestion will be better. Please also discuss this with your doctor. Take care!
I've been injecting methotrexate since January for RA. I'm at .8 - which I think is 20mg. I also take plaquenil. I still have pain migrating from joint to joint and I don't feel any improvement and my CRP keeps climbing. The joints that are bothering me burn and ache so badly I can't sleep or sit still.
My question is how long do you give this stuff a chance before trying infusions?
I have very severe pain on a relatively frequent basis, about 2 episodes a month. I am on humira and it seems to be helping all the other symptoms but the pain. My gi doc only ever offers antispasmodic meds. The pain I am feel IS NOT cramping...believe me I know what cramping is. Not sure what to do. Any advice would be appreciated. Before you ask I know it's not an obsruction...
Ya, my joints tend to stiffen and my fingers and toes begin to curl. Full body pain everywhere. Enbrel has been amazing, giving me a 90% normal life almost pain free. I’m scarred because I only have 1 more month supply before I need to refill it. My Employee based Ins copay was 25 bucks for the month. Now I am retired, it’s going to cost me 1,000 dollars a month.
The competition does sell versions of it (Remicade and Humira) but those are just as costly. Humira actually would cost me more.
My BD has been maintained by Humira 40Mg weekly and Imuran 200Mg daily for over a year. Prior to that Humira was bi-weekly for about 8 months and Enbrel was used for about 8 months prior to it. All in combination with Imuran 150Mg or 200Mg. During this time I have had uveitis (lasted for about 4 months) followed by gastritis (8 months), followed by strep throat leading to chronic tonsilitis and re-occuring bronchitis flares for 6 months that triggered asthma and now back to uveitis...
Pain started in hands and feet. Now every joint is effected. My pain will come and go. Will have it awful for several weeks and then it is gone, last time for months. Then it comes back worse than ever. Last round my knee hurt so bad it would not have hurt more if someone would have hit it with a sledge hammer. No one understands the pain I am in. They all think it is in my head. Of course several doctors mentioned that I was depressed and under stress. Well who isn't now days?
Thanks so much for your input!!! Could you share the dosage amount of both please.
what area of your feet? I have a severe tibial tendonitis/arthritis in the joint and won't have the surgery unless I cannot walk .. in my case, they said no guarantee it would even work and the recuperation is 4mos. Instead I wear high top sneakers 18hrs a day and orthotics and live on Mobic and with change in lifestyle, doing pretty ok with it.
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