Humira and joint pain
Common Questions and Answers about Humira and joint pain
humira
As you well know Humira is an immuno-suppressive
drug , which mainly inhibits TNF (tumor necrosis factor).
There's a growing amount of evidence of the development of Autoimmune conditions, related to TNF inhibitors, such as Remicade, Humira and other biologics.
I took my first Humira shot in my leg on Monday and last night my leg began to hurt really bad. It is a pain that is hard to describe. I told my husband it was a "bone pain" it hurts down deep in the bone from my knee to my hip joint. Today it is hurting mostly in my hip joint.I take darvocet daily for pain and it really isn't helping and neither is naproxen. Is this normal after the first few days of the injection?
I have been treated for rheumatoid arthritis with Humira for 7 months including a combination of Humira and methotrexate for the past 2 months. I also take 5mg of prednisone, and 6 Azulfadine tablets each day. I was taking Humira once every fourteen days and I am on 15mg of methotrexate a week. About a month ago, I started experiencing numbness in my toes and feet. I mentioned it to my rheumatologist but she wasn't concerned and simply told me it wasn't rheumatoid arthritis.
Same deal, more cortisone shots,etc. And just like that, pain has come and gone moving around different joints in my body. R/ elbow then L/elbow, hand, wrist, shoulder, toes. At the present time, I'm 41 and still in pain, still seeing rheumatologist. Diagnosed with RA. (have seen 4 drs. in the past 8 years). I have had all the blood tests which have been all in normal range. No RF present. Negative Anti-CCP. etc etc.
But the joint stiffness and crepidess is still there and i get break through pain even though i still take 600-1000 mgs of ibuprofen a day. I was given percocets and vicodin to take for the break thru pain, but they are poison, addicting and i was developing a very high tolerance to the drugs, which scared me straight into not taking them anymore. My question is this, i have never been really diagnosed with anything other than, "we really don't know".
My BD has been maintained by Humira 40Mg weekly and Imuran 200Mg daily for over a year. Prior to that Humira was bi-weekly for about 8 months and Enbrel was used for about 8 months prior to it. All in combination with Imuran 150Mg or 200Mg. During this time I have had uveitis (lasted for about 4 months) followed by gastritis (8 months), followed by strep throat leading to chronic tonsilitis and re-occuring bronchitis flares for 6 months that triggered asthma and now back to uveitis...
statistically 1 out of every 2-3 of us has hsv1 and 1 out of every 4-5 has hsv2 - a lot of folks who take humira, are already going to have herpes whether they know it or not! Of course you also can contract herpes simplex, either orally or genitally, while taking humira too.
It also can cause shingles to occur - you'd have to have had chicken pox in the past before starting humira in order to have a shingles reactivation.
My rheumatologist put me a=on a drug called plaquenil for 6 months asnd it helped the joint pain about 90% and this was 10 years ago and I have never had a severe boat of arthritis since then. I do still get some joint swelling and slight pain...more like stiffmess. She explained to me that in some people who have long-standing hep C, the antibodies tend to go awry and settle in the joints causeing slight swelling, hotness, redness and sometimes fairly severe pain.
t take what you learn too much to heart. Mtx, Enbrela and Humira have been around for years (esp. the mtx - like decades) and their effectiveness and side effects are well known. Regular bloodwork is required and if anything look iffy, you can stop the meds right away with no harm done.
Once you hit on that combo, you'll know it and the wait will have been worth it.
Again, be the squeaky wheel.
Unfortunately, yes, these are side effects of humira. Cold and flu symptoms are listed as common. From drugs.com: Common side effects of Humira include: upper respiratory tract infection, headache, injection site reaction, skin rash, antibody development, sinusitis, and pain at injection site. Other side effects include: urinary tract infection, abdominal pain, and flu-like symptoms. https://www.drugs.com/sfx/humira-side-effects.html I'd tell your doctor you are experiencing this.
Doctors do not seem to have answers for what we confirm mystery illnesses, but I really want to pass on to you some information that you can read for yourself and keep in mind that knowledge is power. A book published November 2015 it is a must-read for people like yourself and I with joint pain mystery illnesses such as fibromyalgia and the like. The name of the book is called the medical intuitive. The author is Anthony Williams.
I had my gallbladder out two years ago and felt awesome since even went down in humira dosage. My husband and I had issues getting pregnant so we did IVF and sure enough it worked! Got positive confirmation in July 2013 and stopped humira that month. Symptoms started August 23 2013. It started off like acid reflux which they said was normal due to pregnancy take lots of tums and GI doc put me on extra strength omperzole. I got no relief!!
I have ankylosing spondylitis and just had my first Humira shot 2 days ago. Today I woke up feeling very achy, my nose is stuffy and my throat is scratchy. I don't know if it's allergies, an infection, or a side effect from the Humira. Has anyone else had this happen shortly after starting this drug? I am planning to call my doctor on Monday but just trying to figure out what's going on.
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