High dose solumedrol for transplant
Common Questions and Answers about High dose solumedrol for transplant
solumedrol
Im taking a 5 day course of high dose steroids for my relapse. I get the dose in the morning and notice my pulse rate slowly rises during the day . At rest it is 95 and I can hear my heart pounding while I am trying to sleep which makes me more anxious. My chest feels sore too. I keep generally very fit and healthy apart from RRMS and my heart rate is only this high normally when I am recovering from exercise. My BP is good thankfully.
From what I have heard, they like to do high dose IV Solumedrol and can only be done in the hospital setting during a MS exacerbation, especially if the MRI shows enhanced lesions. That is my understanding -- I can be wrong. I do not think the medrol dose pack could touch the effects that high doses of Solumedrol IV could do.
Your job will not allow you to take care of your health? Are you out of personal time off you can take or sick time?
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I'd be checking back with your neuro to find out his rationale for high dose steroids. I'd also be talking to him about a referral for a consult with a neuro who specializes in MS treatment. The field is presently evolving at a fairly rapid pace and we need to have contact with docs who are familiar with what's in development and what's best for our particular situation (those aren't always the same thing).
My high level of GGT after 6 months is what led the dr.s to send me for a biopsy.
Like you I do not drink. don't do drugs ,smoke , If I were you I would be concerned, and get the tests done again ,also if they ask you to get a biopsy DO IT. Unfortunately it is to late for me to do anything , I have cryptogenic liver disease. So I am now on a waiting list for a liver transplant. I hope a second test will show it to lower.
It is unusual for a person to be taking oral prednisone for chronic obstructive pulmonary disease (COPD), especially in a dose as high as 20 mg daily. That dose puts you at risk for a lot of steroid side effects, such as muscle weakness, bone thinning, cataracts, fragile skin, hypertension etc. You should ask your doctor why you need 20 mg of prednisone. You may also want to consult with a lung specialist about this and other inhaled medicines available to people with COPD.
To help with sudden and severe balance problems, and leg weakness in January, I had the mega dose oral steroids for 3 days followed by the taper off. That didn't help, so I had the 3 day mega dose IV solumedrol. I did not do the tapering off pills, because I was having a reaction to the medicine. Since the end of February my ankles are swollen everyday, all day. I asked my neurologist, and she said it is a side effect of the solumedrol. Any one else experience this.....
I do think, just from reading that one site that there are bigger risks associated with acthar, than there are with IV Solumedrol. The high cost would make insurance less likely to aprove usage if there is a cheaper and more widley accepted alternative available, which might explain why you didnt find anyone on it.
Cheers.......
I am 38 years old and have battle allergies my life but began get huge hives a few years ago. After many allergy tests and rounds of prednizone, it was my allergy doctor who realized that I probable had high Ige levels....and blood work proved him right. I began my first series of Xolair with very high hopes. It worked great...but I rebound higher after each series. Normal levels are under 150...I started off with just slightly higher at 183. This was a couple years ago.
I used them monthly for over a year with Rebif. I also was not given a taper dose. I began with three infusions every four weeks then went to three infusions every four weeks. Nothing slowed my symptoms down. I did use five days of Actar Gel but it didn't work for me. I guess my body just began rejecting the steroids. Long story short I began Tysabri. I had my first dose. I ended up in the hospital for thirty days. I was given IVSM again.
I did eventually feel a bit better overall, so maybe it was worth it. Even the one day dose makes me feel pretty lousy. My sx actually seem to get worse for a few days afterward!
I'm not dx, but symptomatically fit the diagnostic criteria (we'll see what the 3T MRI has to say...) If the steroids make me feel worse for a few days, does this suggest that it's not an inflamatory process causing my sx? Anyone else feel worse after solumedrol?
How long can it take for solumedrol to take effect?
You say you have Autoimmune Hep, Hep C, Fatty Liver Disease, Stage 4 Cirrhosis, and type 2 diabetes.
This is a very unfortunate combination of issues. Autoimmune Hep, Hep C, Fatty Liver Disease all contributing to your liver disease.
Hopefully your hepatologist by treating your hep C can slow the progression of your cirrhosis while trying to manage your other illness as well.
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Hi, Kiddo! I have heard some people here (undiagnosed) say their symptoms were helped a little by a DosePak. However, it is unlikely that MS will respond to one, except possibly very briefly, and here's why:
Medrol (methyprednisolone) is identical to Solumedrol, but is the oral form. When we get IV infusions we get 1000mg of it. Each pill in the dose pack is 4 mg. You take 6 tabs the first day, and then 5, 4, 3, 2, and 1 the following days. (24mg, 20mg, 16mg, 12mg, 8mg, 4mg).
Thank you Laura. Perhaps that is his thinking b/c my MRI showed no new spots and no active spots. It's mystifying to me that each time I experience symptoms my MRIs do not change. I'm thankful, don't get me wrong very grateful. It's just that I feel crazy for having the symptoms. Nonetheless I have them. Thank you for your perspective on my comment as it seems apt on.
s biopsy and lab numbers clearly show him heading down the road to fibrosis and cirrohsis, would it make sense to push for trying the new drugs at least the approved ones for non-transplant such as teleprevir and bocepavir? Otherwise the patient is looking at another transplant which would seem to be quite a negative option.
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