People with lupus of mixed connective tissue disease
are at higher risk for develping coronary or valvular heart
disease. Given that your symptoms have been going on for some time now, albeit, atypical probably warrant further workup. The most concerning would be the chest pain, although, you describe it as atypical. Unfortunately, women tend to present atypically and I would hate write this off to something else without doing a thorough work-up.