The IR and beta-cell function were evaluated by
homeostasis model assessment of IR (HOMA-IR) and
homeostasis model assessment of beta-cell function (HOMA-beta) before treatment.
RESULTS: HCV genotype, pretreatment HCV RNA level and pretreatment HOMA-IR, but not HOMA-beta, were independent factors associated with sustained virologic response (SVR). In 150 patients with genotype 1b infection, pretreatment HCV RNA level, HOMA-IR and age were independent predictors for SVR.