For the arthritis conservative measures are
weight loss, rest, ice, canes, bracing, physical therapy. etc. Also, nutrition supply should be considered, with chondroprotective agents (glucosamine & chondroitin phosphate, MSM, Omega-3). Glucosamine and chondroitin phosphate are unlikely to cause any drug to drug interactions with your other medications. But to date, there has been no evidence of structural improvement with these conservative modalities.