These data suggest that further meticulous studies are required to determine the criteria for dose reduction and to define the use of G-CSF for PEG-IFN-induced neutropenia.
------------------------------------------------------------------------------
In this study 2876 patients:
http://www.ncbi.nlm.nih.gov/pubmed/20830784?dopt=Abstract#
Bacterial infections during treatment with peginterferon alfa and ribavirin are not associated with neutropenia.
Do you mean filgrastim? And are you saying Dengue fever? It would be a surprising though perhaps not impossible use of filgrastim. Dengue is usually treated by pain managers and sometimes hospitalization and a blood transfusion.
Anyway, if you have a legitimate prescription from a doctor, you should be able to fill it in the United States.
For this reason, patients are prescribed antibiotics and even receive injections to increase white blood counts (such as filgrastim or lenograstim).
If this 0.4 value really pertains to your white counts, then I believe this is really low and what you are experiencing is a condition called 'febrile neutropenia'. I would suggest you ask your doctor about filgrastim or lenograstim injections aside from the Levaquin.
Regards.
You can ask your hematologist for G-CSF injection if you have persistent neutropenia. Patients with CML are immunocompromised and can easily acquire infections. Neutropenia also puts a patient in an immunocompromised state.
For now, it is very important to prevent acquiring any infection. You should avoid crowded places and persons with ongoing infection.
Good luck.
In the absence of data, reduction in IFN dose and/or G-CSF dose for those who develop neutropenia while undergoing IFN-based therapy for HCV infection are often initiated in clinical practice, as suggested in treatment guidelines [6] and mandated in most clinical trials [15]. Reduction of IFN dose is well accepted to have a detrimental effect on the rate of sustained virological response [2].
This headache is completely different to what she was experiencing before the lumbar puncture. Initially, doctors suggested this was a low CSF pressure headache due to too much CSF fluid being taken during the lumbar puncture.
The blood patch was done 3 weeks after the lumbar puncture and provided approximately 12 hours of relief, and enabled her to stand up without too much trauma.
Filgrastim is also prescribed as pegfilgrastim (called Neulasta). My doctor used the 500 neutrophill count as a cut-off, so every time I got down around 500 I used Neulasta. The interferon drops neutrophils and platelets. Some people can do okay with low neutrophils but just as many end up with kidney and sinus infections, etc., that make you even more miserable.
My sister has a CSF leak and I'm looking for a doctor on the East coast that specializes in finding and fixing CSF leaks. Any help would be greatly appreciated.
Thanks!
The Panel reaffirmed that positive cerebrospinal fluid (CSF) findings (elevated immunoglobulin G [IgG] index or 2 or more oligoclonal bands) can be important to support the inflammatory demyelinating nature of the underlying condition, to evaluate alternative diagnoses, and to predict CDMS.
This is an excerpt only. I'll post the entire revision in a separate post.
Doctors unable to give any explanation for such wide variations on a dose to dose basis. Till date, I have also taken 5 doses of Filgrastim - the WBC Stimulator.
Can you pleae advice possible reasons for such wide fluctuations.
Recommended
