ezetimibe uk

Not a question, just to say how the recession in the UK has affected me. I am no longer allowed to have Ezetimibe prescribed due to NHS cuts. My total cholesterol was 146 when taking this with statins, and my blood test this week reveals total cholesterol of 220 which is a tad above the national average of 212. I hope the higher cholesterol doesn't cause my arteries to start blocking again.

also statins like simvastatin were reported to boost response a little but better not mix 2 statins, in a report researchers of ezetimibe effect on hbv and hcv suggested the use of ezetimibe with interferon but without simvastin ezetimibe dose is 10-20mg daily but human trials with dose 50mg daily for a limited time did not find any sides or toxicity

The FDA-approved drug ezetimibe (sold under the trade-name Zetia) is readily available and perfectly targeted to the receptor, Sainz said, so the researchers had an ideal method for testing NPC1L1's involvement in HCV infection. The researchers showed that ezetimibe inhibited HCV infection in cell culture and in mice transplanted with human liver cells. And, unlike any currently available drugs, ezetimibe was able to inhibit infection by all six types of HCV.

You could consider going for a higher dose of Lipitor, another way to go is to consider taking a drug that limits cholesterol absorption such as Ezetimibe. There is a combination drug Simvastatin and ezetimibe that may be better in controlling cholesterol. Discuss these drugs with your doctor. Best of luck to you. Stay positive.

A recent paper studied the effect of most FDA approved drugs on the inhibition of NTCP, the now known entry receptor for HBV. Ezetimibe was found to have a 50%inhibition conc of 25micromolar, while irbesartan, a commonly used angiotensin inhibitor to reduce blood pressure, was found to inhibit at 11.9 micromolar. Both compounds have similar MW, but irbesartan is given at up to 300mg per day, while exetimibe is dosed at 10mg.

no study for its activity on hbv, we do know it has activity but the trial has never started simvastatin lowers hcc 50% and prevents fibrosis/cirrhosis so it is indicated on all hbver, this has thousands of pateints studied for decades to find this data on hcc you better use simvastatin instead other statins, also ezetimibe has in vitro effect on hbv so these are the best choices on hbvers

The UK has decided that LDL should be between 3-4 mmol/L and yours is 2.06. I would watch for symptoms such as finding concentration hard with it so low. Your HDL should be greater than 1.0mmol/L and is 0.8. However, with such low LDL, this ratio is fine. Your trigs should be lower then 1.4mmol/L and are 2.91 which is far too high. Your very low density lipoproteins are also high, these are recycled by the liver, having one of the proteins on the outer membrane removed, to become LDL.

I was put onto a strong aggressive statin (lipitor 40mg) and ezetimibe 10mg to help boost it. One act son the Liver and one on the digestive system to lower fats. I had my first attack at 46 and my disease kept progressing. I cut my sugar intake right down, took lessons in handling stress and then my disease seemed to stop. Even with high average blood pressure 140/99 - 140/103 the disease still hasn't got any worse.

ldl cholesterol in april was pretty high, too high for heart disease. In the UK they aim for a maximum ldl of 134. Trigs max is 154 Hdl min is 57 I think the cardiologist or gp should be looking more aggressively at reducing his cholesterol. What dosage of crestor is he on?

There was an in vitro study on ezetimibe inhibiting HBV DNA production. The ed50 was fairly low and in a similar range as lamuvidine. So it looked very interesting. But in an in vitro study you have a constant exposure to the drug, which is impossible to achieve in vivo. And the cells used are not the same as regular hepatocytes in human liver, with many differences in gene expression and cellular physiology.

I was given an additional medicine which dramatically decreases the absorbtion of fats through the digestive tract. This is called Ezetimibe and just 10mg reduced my cholesterol a great deal. Maybe your GP could look to attacking your problem from this angle?

About two years ago my doctor added ezetimibe to my regimen. It has been lowering my bad cholesterol how ever the first of this month I missed taking them for about a week and for the first time in years I felt less fatigued. I do have Fibromyalgia which is usually the cause of my fatigue, but this is a different type of fatigue. I have not restarted either of the cholesterol meds back because I have felt so much better. I know I need to talk to my doctor about it.

Any mummies on here from the UK? im a FTM and just had my 20 week scan..

Is any one from the UK?

I was just wondering if any one is from the UK on this app?

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