How does ezetimibe work
Common Questions and Answers about How does ezetimibe work
vytorin
also statins like simvastatin were reported to boost response a little but better not mix 2 statins, in a report researchers of ezetimibe effect on hbv and hcv suggested the use of ezetimibe with interferon but without simvastin
ezetimibe dose is 10-20mg daily but human trials with dose 50mg daily for a limited time did not find any sides or toxicity
I have been taking 2000mg Niaspan daily for the last 18months, helping to raise it from 25 to 30. I run about 9miles a week, work out 3-4X at the gym each week, and drink a glass of red wine every night. I eat nuts every day, take Omega3, and rarely eat red meat - subscribing to a low cholesterol diet. Weight is 185 at 6'3", age 50. LDL is always pretty low - most recently 66.
This paper is also fascinating, since it clarifies the mystery, recently discussed directly in the ezetimibe thread, how ezitimibe works to block Hbv entry, as shown by ulrike prozer in the hepaRG system. It is simply a NTCP blocker, moderatly potent. Of note, blockage of this receptor, NTCP, is also the mechanism by which Myrcludex works as an entry inhibitor. It is the membrane protein that normally transports bile acids from the portal blood into the hepatocytes for recycling.
Thank you. Have lost considerable weight since bilateral orchiectomy in 2005 and over the last 6 months, 5' 11" under 170, no signifigant girth. No family history of diabetes, significant history of heart disease. Cholesterol levels were well maintained until June 2008, no indication of blood sugar elevation either, until now. BP is good, slightly higher in last year but was well below norms until now.
I live in Canada and I see here that everyone seems to talk about cholesterol numbers in 100s, where here in Canada they seem to use a different system to show counts. Does anyone know how to convert these numbers to the numbers that the US goes by so when I read these posts I can figure out where I fit in?
here are my numbers:
Cholesterol 3.84
Triglycerides 1.04
HDL 1.37
LDL 2.0
TC/HDL-C Ratio 2.
Only around 20% of the fat in your blood comes from food, the Liver can make fat by itself and does. Without statins my total cholesterol is 375-400. With 40mg of Atorvastatin accompanied by Ezetimibe, It is 160-162.
It has to be said though, more and more research is revealing that fats have little to do with it. I don't think it will be much longer before they finally find the culprit.
About two years ago my doctor added ezetimibe to my regimen. It has been lowering my bad cholesterol how ever the first of this month I missed taking them for about a week and for the first time in years I felt less fatigued. I do have Fibromyalgia which is usually the cause of my fatigue, but this is a different type of fatigue. I have not restarted either of the cholesterol meds back because I have felt so much better. I know I need to talk to my doctor about it.
m not certain who told you to restrict your daily intake of oil to 15g? but it does seem a little absurd. Oils are unsaturated fats and the fats you should be reducing are saturated, and of course, avoiding trans fats at all costs. It is also worth considering that we all absorb fats at different rates and only around 15-20% of fats we eat ends up in our blood, the rest is recycled or made by the Liver.
They are suppose to strip my membranes how does that work? Does it hurt.
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