Etanercept and infliximab
Common Questions and Answers about Etanercept and infliximab
enbrel
Our aim was to investigate the efficacy and safety of etanercept as adjuvant to interferon and ribavirin in treatment-naive patients with HCV. METHODS: Double-blind, randomized, placebo controlled trial. Fifty patients with chronic HCV were randomly assigned to receive interferon alfa-2b and ribavirin with either etanercept or placebo for 24 weeks. The main outcome measure was the absence of HCV RNA at 24 weeks, the on treatment response at the end of the etanercept randomization period.
Can a perispinal etanercept injection help heal severe pain linked to the piriformous muscle?
Liver failure occurred in 5 patients, 4 of whom died. The drug Infliximab caused the highest rate of HBV resurgence and liver damage, compared with the drug etanercept in this group.
Among core antibody people, with resolved infections: Reactivation occurred in 9 (5%) cases, including 1 patient who died due to liver failure.
I have had a sore throat for a little over a week now accompanied by dizziness, vomiting, headaches, and runny nose. I was sent to the ER last night by an urgent care doctor because she thought I might be having a flare-up of Crohn's, since I also had a fever. I can't see my primary care physician right now because I'm out of town. They sent me home saying it was a viral and I should be better in a couple of days.
Hi!
Well, peri spinal etanercept is a relatively new therapy for sciatica type of pain. However, as with any new therapy, it has its success and failure stories. It is however known to penetrate the spinal fluid and cause rapid relief in pain. The negative side is that there is no pain relief (which actually cannot be a negative side as you are already in pain). As a note of caution: this mode of drug delivery with etanercept is still in late experimental stage.
Question was posed to her GI doctor and they have not offered an opinion. Optometrist does not know, and ophthalmologist will not respond b/c she is not yet a patient. The remicade infusion has been delayed once already (due to illness) and we do not want to delay the infusion any longer than necessary and risk a UC flare up. Any information on RCE and the affects of infliximab would be appreciated.
I visited my dr who said l had blood in urine but nothing to worry about and said apotential UTI and gave me antibiotics after suffering for three weeks, l am now getting much worse, on my last visit on Wednesday there was less blood in my urine, no temperature BP normal but had protein and she gave me more antiobiotics, augmentic for a further seven days and 400mg of an anti-inflammatory drug one three times a day.
I have been on methotrexate for over 20 years and also have been on etanercept (enbrel) but now am only on methotrexate, celebrex and infusions of rituxan every 6 months. I read about all the adverse reactions of all the meds I take and these have never been associated with either of your meds.
it could be the vitamin d and calcium deficiencies. best of luck to you.
hi
i'm 15 and i have crohn's disease. i'm portuguese so i apologize for my english. i'm going to start a treatment called infliximab and i wanted to know if it's ok for me to continue smoking weed. i started smoking weed 10 month ago and nothing changed but i'm scared of starting this new treatment. i don't smoke a lot but i don't know the side effects of the 2 combined. i can't ask my doctor because my mom is always is me.
I have not taken it since and am continuing on infliximab infusions 8 weekly, with codeine phosphate (to slow my motility) and imodium instants to try and control the morning diarrhea. Winning some days, other days the diarrahea is bad after my first food. Gastro has explained that the sympathetic nervous system goes into action when eating food (no matter what it is, even a simple slice of toast) and this starts the mnotility in the intestines.
The standard therapy options include intravenous immunoglobulin and plasmapharesis, corticosteroids, azathioprine, cyclophosphamide, etanercept, mycophenolate mofetil, interferon alpha 2a and tacrolimus. Current ones are interferon beta 1a, rituximab, and high dose cyclophosphamide. Your neurologist needs to apprise you of the long-term side effects since prolonged therapy are required. Botox shots are not known to be used in therapy.
Which is why so many of the biologic drugs used for those conditions, such as adalimumab (Humira), etanercept (Enbrel), and infliximab (Remicade) show promise for HS sufferers."
***
Excerpts from "Putting Hidradenitis Suppurativa Into Remission"....
"I decided to ask Loren Cordain about HS when I interviewed him at the AHS last summer. He mentioned that he thought HS might have an autoimmune component but other than that, he didn’t have any information.
Background/Aims
Current therapies for patients with chronic hepatitis C virus (HCV) do not achieve sustained viral clearance in most patients, and are associated with severe toxic effects. Our aim was to investigate the efficacy and safety of etanercept as adjuvant to interferon and ribavirin in treatment-naive patients with HCV.
Methods
Double-blind, randomized, placebo controlled trial.
s flares, it goes up really high - 6 weeks ago mine was 190 and I needed to be hospitalised for dehydration and to recommence Infliximab. When I had a really bad flare last year, some 6 months after my first resection (right hemi-colectomy) it was an incredible 260 - my gastro treats a lot of Crohn's and UC patients, and he said he had never of a C-RP being so high. IV antibiotics, methotrexate injections and Infliximab infusions brought the level down, but it was touch and go at the time.
t stop me getting bc, and currently on weekly self administered 25 mg injections, since I switched from 2 yrs of Infliximab. I stopped the infliximab because of severe inexplicable weight gain and have now got my weight back to normal at 120 lbs - I am only 5' 2".
Over the years I think I have tried most drugs to keep the disease in remission and now find methotrexate has the least side effects which are tolerable.
s (Infliximab, Humira) which I started last July, so at least he is current with all new drugs. and....I trust him implicitly.
Protein? I have always had to follow a high protein, high carb, low fibre diet, so I tend to eat very little red meat, but lots of fish, chicken and game. I occasionally have calves' liver, because I like it, and it has a lot of iron.
I was on mtx tablets 25 mg weekly, then 25 mg injections (done at home weekly), but after having some serious flares and surgery (right hemi-colectomy) 3 yrs ago, I was put on Infliximab infusions, every 8 weeks as a day patient in hospital. This caused enormous weight gain and I have just recently gone back onto mtx 25 mg injections which is working okay.
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