I bought an over-the-counter cream of Estriol
USP, which has less than .75% of Estriol per pea-sized amount. As soon as I used it on my abdomen, I began having the normal symptoms I would expect with my period, which brought me great relief. My flow was then normal. It had not been for two months. The next two days I used the cream on my arm, and then my inner thigh. When I used it on my arm, for a couple of hours I had muscle pain which then moved to my arm bone below the affected muscle.