s reaction to the Lyme bacteria, the PCR test looks for DNA of the Lyme bacteria in your blood -- that is, a direct test, rather than an indirect test like W.blot/ELISA.
Docs who are not particularly up to date on Lyme do not 'believe' in the PCR test but do believe that W.blot/ELISA is fully accurate. If you need help finding a Lyme specialist who understands all this, let us know.
(If this is a duplicate message from me, just ignore ... I thought I had responded.)
I'm not medically trained, but I had Lyme several years ago, and your symptoms are quite similar to what mine were ... but Lyme is tricky, so not everyone has the same list of indicators.
I was tested for lyme disease over a year ago by my family physician. Test results came back negative. I was reading an article in a magazine concerning symptoms of lyme disease and everything listed as symptoms I seem to have. I am trying to find a specialist in my area who is knowledgable in this area. Should I have another blood test done to see if things have changed?
Borreliosis can be extremely threatening if it is not diagnosed and treated in early stages. Kidneys are not typically involved in the disease. However, in infected dogs, Lyme nephritis is present in 5–10% of cases. It is associated with rapidly progressing renal failure.
Histopathological examination shows mesangial proliferative glomerulonephritis with diffuse tubular necrosis, (Dambach et al. (1997)).
The IDSA guidelines use a 2-tier blood testing scheme for detecting Lyme. In the 1st step, the ELISA test is used. This is like a screening test. If (and only if) the ELISA is positive, the 2nd step is to do a Western blot test, which looks for certain antibodies in the blood that are (mostly) specific to Lyme disease. There are criteria for how many "bands" (each band is like a different antibody) must appear on the Western blot to fit the CDC definition of positive.
the ELISA and the Western blot. Doctors commonly order an ELISA first to screen for the disease and then confirm the disease with a Western blot. However, current ELISA tests are not sensitive enough for screening and may miss over half the true cases. Because of this, the best antibody test to use for diagnosis is the Western blot. ...
"Western Blot Test
"The read-out from the Western blot looks like a bar code.
Thats a difficult question. Elisa lyme test a is common test doctors use to diagnose Lyme. It test for the antibodies in your blood. As well as the Western blot test which is usually used after Elisa to confirm. Western blot is more accurate, but the accuracy rate among these types of test is about 40-60% depending on when you contracted the disease. The best way to rule out Lyme's is to see a LLMD doctor who specializes in Lyme and can run a specialized panel.
You want to know about Lyme disease then I suggest you go to a forum that discusses it.
It is the CDC ELISA test which is used for surveillance of emerging Lyme disease in the United States, yet the test was correct only about two out every three tests. Too often, a single negative ELISA test can prevent a sick patient from getting treatment, even despite having serious symptoms! "
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Hi Goldie23
You are asking good questions --
I'm guessing FMS means fibromyalgia? MPS and DDD I don't know. Lyme patients are sometimes told they have fibromyalgia, a disease syndrome with no known cause or cure. We do know however that Lyme is caused by a specific bacterium and is treatable.
you can have Lyme, but the test can show negative, since the ELISA/Wblot test can be fooled into not detecting the immune reaction.
By contrast, the newer and differently structured IGeneX test doesn't play hide-and-seek like ELISA/Wblot does: instead, IGeneX looks for Lyme genetic material (DNA) in your blood, which is a direct test and no fooling around playing hide-and-seek.
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