dipyridamole vs adenosine

While adverse effects are less frequent with dipyridamole (47% of patients), they tend to be more serious than those associated with adenosine. The most common adverse effects of dipyridamole are chest pain (19%), headache (12%), and hypotension (4.6%). In addition, 12% of patients require aminophylline for reversal of adverse effects.

False negative imaging is especially common when exercise is submaximal or in dipyridamole/adenosine studies of patients with severe obstructions of all three major coronary vessels. False positive scanning may be caused by signal attenuation from an elevated left hemidiaphragm or from breast tissue. These artifactual defects can be identified by performing a gated perfusion study to assess regional wall motion.

Both drugs are some what the same, they both work by keeping your blood platelets from sticking together and forming clots. Plavix is a adenosine diphosphate (ADP) receptor and Pradaxa is a direct thrombin inhibitor. Both do basically the same thing just in different ways.

Persantine is dipyridamole, but you will have to get extended release tablets as the two asprin and dipyridamole should not be taken together. Don’t change the medications without discussing with your doctor. So, consult him and then decide. Hope this helped and do keep us posted.

I have read that Caffeine is almost Identical to Adenosine and that caffiene can block Adenosine from being effective as it should be as it sits in the Adenosine receptors, could this be why it was not effective the first few times as I had been at work all day consuming lots of tea and Coffee yet on the occasion the SVT was stopped with Adenosine I had not had 1 cup all day.

What is nonreversible apical inferior wall and what does it mean when they say no dipyridamole-induced reversible ischemia .there is mild defect in the apical inferior wall that is not reversible at rest.

While you are taking Aggrenox (aspirin/dipyridamole), you should avoid taking over-the-counter pain medicine, especially any other products containing aspirin or non-steroidal anti-inflammatory drugs (NSAIDs). Also, Avoid alcohol, or drink a minimal amount, as the combination of Aggrenox and alcohol could cause stomach bleeding.

Some of the alternatives include aspirin, Clopidogrel (Plavix), ticlodipine (Ticlid), dipyridamole (Persantine). Another alternative is Heparin injection. Different situations require different levels of anticoagulation. It is important to discuss the best treatment option with a physician.

I just looked adenosine up and it specifically states that it is not effective in converting anything but PSVT to normal sinuse rhythm that it does not work with atrial fib or flutter.

My mom went to see a Heart Specialist and he recommended the Adenosine Stress Test. She is not having any chest pains, but this he said would make sure there are no blockages. I would like more information about this procedure and is it dangerous? Another doctor had recommended a stress test that involved putting something in her veins and it would make her heart speed up. This Heart Specialist said no, and that this Adenosine Stress Test is not the same thing.

I suffered a mild stroke (blood clot) Consultant prescribed Clopidogrel but cannot tolerate side effects. Then consultant prescribed Dipyridamole. I cannot tolerate this either. Severe headache, vomiting and diarrhoea. Has anybody got a different medication they are on?

I am more afraid of the sensation of having the SVT than of the Adenosine to cure it. Yes the Adenosine feels awful but the relief I feel when my heart resets - emotionally - makes the Adenosine sensations worth it. I've had Adenosine 7-8 total in my life and the very first time I had it was probably the scariest. All other times I was actually asking for it by the time the medics arrived.

I recently had an exacerbation of svt requiring adenosine and an increase in my maintenance metoprolol dosage. I essentially lost a day of memory and have been forgetful and foggy headed. Just wondering if this is normal. I can't get any doctor I have seen to address this.

Thankyou for your response. I wanted to mention that I also had a nuclear adenosine stress test in July of 2010. I had just started taking metoprolol at bedtime in addition to the lotrel and hyrochlorthiazide. The cardiologist said to take it the night before the test since It was an adenosine test instead of treadmill testing. The conclusions of the Dr. were ejection fraction of 49% after administration of adenosine and no abnormal segmental wall motion abnormalities.

My rx says adenosine nuclear stress test. Adenosine is used in lieu of exercise.

Caffeine blocks Adenosine (which is a neuromodulator so it moderates neurotransmitters in your brain, causing dilated blood vessels and basically,pain) so caffeine has the opposite effect, it constricts blood vessels and increases the release of excitory neurochemicals in the brain.

In the past, I've confused my SVT with anxiety or panic attacks. Whenever I get really anxious, I constantly fear I will go into SVT and have to go to the ER. I hate when you have to get the shot of adenosine in the ER :( I've also never had panic attacks prior to being diagnosed with SVT. So me knowing I have SVT causes me anxiety and then leads to a panic attack. Any insight on this matter? Maybe on how to distinguish between the two? How to calm down?

thallium mibi stress scan..... i was not able to pass the stress test ... they injected adenosine and i got fast heart rate and pani attack they had to stop the test.... then the doctor said we will use treadmill for stress ( it will be done after some days) i was ashamed that i couldn't pass the stress test i was embarrassed..............cardiologist has said that you need to see a psychologist asap...... i have sleepless nights always thinking about my brother......

I have a little cycle where I have a PSVT episode requireing the Adenosine IV, then I get anxious about having a PSVT episode requiring an Adnosine IV, which of course, causes me to be anxious enough that I am more likely to have one. My anxiety always seems to go up around the same time I have a cycle of a few PSVT episodes - and this cycle reoccurs every few years.

ECG last month showed SVES, RBBB. This week he has stress test with dipyridamole protocol, and injection of thallium-201. The result showed "evidence of mild, small to medium size, irreversible perfusion defect in the inferior/inferolateral wall (mid to basal level)." Could you explain what this means? Does he need to have surgery or pacemaker? thanks in advance for your help.

I just came across and article that says "Adenosine and other AV node blockers should be avoided in atrial fibrillation and atrial flutter with WPW or history of it; this includes adenosine, diltiazem, verapamil, other calcium channel blockers and beta-blockers." And my son is on atenolol for WPW. Should I be concerned?

My SVT before my ablation had me in the ER...with an adenosine push. The last one was in Dec 07 and they had to push adenosine twice before it brought my heart rate back down. The time before that, one injection and that was enough. The one in Dec. I was on beta blockers, so I thought one injection would do the trick but it didn't I was very nervous at the thought of them starting my SVT during the ablation, but I was not awake and didn't know a thing.

later 12mg of Adenosine to get the heart rate down. She will be visiting a cardiologist in 2 weeks. In the meantime, she still continues her daily medication. However her heart rate seems to be very low 50s (50-55) while resting and she gets tired very quickly. Should she be concerned about the low heart rate? Is she still having the affect of adenosine and should she stop atenolol for a few days? is surgery neccessary for her to eliminate SVT? Is SVT dangerous?

So you got the wonder drug? I HATE adenosine! There is nothing more pleasant than the feeling of a 300 pound elephant sitting on your chest! I would make sure it is SVT first. Have you had an EP study done yet? I have hit 318 beats per minute...Every time it happened they would hyperventilate in the ER!...I have never passed out from it either. I was diagnosed with SVT 2 years ago and for 14 months I was treated for it.

If those measures fail to terminate the SVT than Adenosine, is safe and effective in terminating SVT. It is rapidly metabolized with a very short half-life, making it ideally suitable for use in pregnancy. If adenosine fails, other antiarrhythmics may be indicated and the risk of their use should be weighed against the risk of continuing SVT. Beta-blockers have been used extensively in pregnancy, to treat maternal hypertension and cardiac problems, and are generally well tolerated.

The explaination is really complicated (something about that caffeine blocks the receptors for the substance adenosine which the atria has more receptors for than the ventricles). I don't know why, but it seems like almost everyone here think they have PVCs rather than PACs if they get palpitations. This is not necessarily correct. It seems you are quite bothered with your palpitations, so you should consider seeing a doctor to get this examined (see previous post).

Pharmacological stress Tc-99m MIBI scan was performed with Dipyridamole given at arate of 0.14 mg/Kg/min over 4 minutes followed by injection of radio tracer 6 minutes later. Findings are: Peak stress images revealed hypoperfused infero-septal and apical segment, which showed reversal at rest. Impression: Findings are consistent with infero-septal and apical reversible ischemia. Thanks all!

Dipyridamole vs adenosine

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