Desmopressin and von willebrand's disease
Common Questions and Answers about Desmopressin and von willebrand's disease
ddavp
Hi all,
This is my first post in this community. Following an approximately 8 month (and counting) history of recurrent petechiae, my doctor finally referred me to a hematologist for further evaluation. The hematologist listened to my concerns and told me that she wanted to test me for von Willebrand disease, but she expected the testing to come back negative as I "should have other symptoms besides petechiae if it's von Willebrand's.
She has Von Willebrand's, but hasn't been diagnosed with Hashimoto's (although my family has a high incidence).
When she had her Chiari diagnosed a decade ago, she had syringomelia. No diagnosis of any of the other conditions or bulging disks.
She'll be out of the country till the end of the month...otherwise in great health and not even a thought of the Chiari from so long ago.
Hi!
I just noticed your question -- not sure why it just appeared in the forum, except that the date could be wrong? If you were my patient, the first thing I would do is to check a pregnancy test. If that is positive, then we go down a completely different pathway. If it is negative, then I would want to evaluate some hormone tests and tests for blood clotting disorders such as Von Willebrand's disease.
Hello and hope you are doing well.
Your symptoms could be due to a sinus infection, a cold or a chronic allergy. Your symptom of nose bleeds may also indicate a bleeding disorder. The causes for bleeding disorders are hemophilia, von willebrand's disease, immune disorders, leukemia, aplastic anemia and scurvy. The bleeding can also be due to liver disorders, certain medications like blood thinners and non steroidal anti inflammatory agents.
I got some bloodwork im concerned about what it means. I'm a 22 year old female. Most concerning, my B12 levels were very high (1373 pmol/L) (I don't take supplements). My RBC and hematocrit were also high. Cholesterol was also high (very unusual, I'm almost nearly deficient and I eat healthy). Ferritin was a little low (not abnormal, but supplements recommended). There were leukocytes in my urine (2+? i don't know what that means).
I got some bloodwork im concerned about what it means. I'm a 22 year old female. Most concerning, my B12 levels were very high (1373 pmol/L) (I don't take supplements). My RBC and hematocrit were also high. Cholesterol was also high (very unusual, I'm almost nearly deficient and I eat healthy). Ferritin was a little low (not abnormal, but supplements recommended). There were leukocytes in my urine (2+? i don't know what that means).
According to medicine net, some causes of easy bruising are cirrhosis of the liver & liver disease, Marfan syndrome, bone marrow disorders, hemophilia, platelet disorders, medications- prescription and OTC- especially aspirin, NSAIDS (like ibuprofen, etc.) & prednisone, and Von Willebrand's disease. See PM for more things that can cause easy bruising.
I'm assuming your vet ran PT/PTT blood tests (which test all of the clotting factors and the time it takes to form a clot), but if only a CBC/Chemistry was run, you should definitely have them send out for a PT/PTT and von willebrand's test (which is a factor important in how platelets form clots to the blood vessel endothelium). Rodenticide toxicity is also on the list and your dog should ideally be treated with 30 days of Vitamin K to be on the safe side.
I got some bloodwork im concerned about what it means. I'm a 22 year old female. Most concerning, my B12 levels were very high (1373 pmol/L) (I don't take supplements). My RBC and hematocrit were also high. Cholesterol was also high (very unusual, I'm almost nearly deficient and I eat healthy). Ferritin was a little low (not abnormal, but supplements recommended). There were leukocytes in my urine (2+? i don't know what that means).
First everybody can miss a period, not to panic. I would do a pregnancy home test. If it were negative, I would make a Gyn appt. I usual don't let my pts go more than 2 months without having a period if they are not on a treatment to take their periods away. The Von Willebrand's is reason to be followed. I would want to control your bleeding for this reason and BE REGULAR.
Usually an increase in a clear discharge is a good sign of ovulation, Could these be your symptoms?
Always have had extremely bad cramps since first getting period but constant bleeding did not start till about year and half ago. Seen two specialist and they say I am out of options to control it and can not find any significant cause! Any ideas why this is happening or anyone else experienced same thing?
I got some bloodwork im concerned about what it means. I'm a 22 year old female. Most concerning, my B12 levels were very high (1373 pmol/L) (I don't take supplements). My RBC and hematocrit were also high. Cholesterol was also high (very unusual, I'm almost nearly deficient and I eat healthy). Ferritin was a little low (not abnormal, but supplements recommended). There were leukocytes in my urine (2+? i don't know what that means).
Might be a bleeding disorder like Von Willebrand's or hemophilia. PT, INR labs would be useful and maybe a hematologist visit might be a good idea.
Hello and hope you are doing well.
The petechiae may indicate a bleeding disorder. The causes for bleeding disorders are hemophilia, von willebrand's disease, immune disorders, leukemia, aplastic anemia and scurvy. It can also be due to liver disorders, certain medications like blood thinners and non steroidal anti inflammatory agents. I suggest you consult your doctor, who may do blood counts, bleeding and clotting time and a prothrombin time, to identify the cause for the petechia.
My Endo wants me to do a biopsy, but I am concerned as I have Von Willenbrands Factor VIII deficiency, and had a bleeding problem in July from a deep tooth scaling (which probably was made worse by going to a dental surgeoun after who probably dug deeper) and I ended up on Amacar for 10 days and two rounds of Desmopressin IVs. In the past, I have had a couple of needle biopsies in the breast with no problems. I will contact my hemotologist, but was also looking for another opinion.
On those days (when he takes two puffs) he only goes to the bathroom 4-5 times the whole day, which is great because I can take him places and get him out of the house. Does anyone know or take Desmopressin more often than one time a day??? If so how many times?? Any information would be helpful!!
But drinking too much liquid with the medication can cause problems, and Desmopressin should be avoided if you have symptoms such as a fever, diarrhea or nausea. Be sure to carefully follow instructions for using this drug.
Desmopressin is given orally as a tablet and is only for patients over 5 years old.
Hi,
You had underwent a thorough assessment and seems like incontinence and interstitial cystitis were ruled out. When was the last time you had a cystoscopy done?
Were you able to get some blood tests done.Hormonal imbalance due to pituitary dysfunction and diabetes may lead to increased urinary frequency( after structural problems like stones have ben ruled out) .Also are you previously taking any medications?
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