Within two weeks, I had joint paint, nausea, fatigue, nosebleeds, bruising, and petechial rash. I took 165mg 80% silymarin
for 14 days and this helped. 5 days after stopping silymarin, my symptoms returned in full. I then had a midnight attack of acute RUQ pain with nausea/vomiting that landed me in the ER. My ALT was 193, AST 183, mildly elevated bilirubin, platelets 172K, neutrophils 94%.