About 6 months ago, I was finally diagnosed and started taking cyclosporine 100 mg 2x day. After a week, I could eat like a normal person—just about anything I wanted. It was great, it even allowed me to travel to Europe. The cyclosporine I was taking was a powder in a capsule, apparently this has been taken off the market and instead I took the same medication, but it was in the form of a capsule with alcohol. Unfortunately, after a short time, I was right back to before treatment.
Yes I took Cyclosporine for my aquagenic urticaria, it helped so much but not enough to have a normal life :S but maybe for you its going to be different...
I am still on 100 mg 2x daily cyclosporine. My cyclosporine through levels have been lower, the last time they were at 79. I Have been on 300 mg ursodiol 3x daily for biliary stricture since tx. I lowered the dose to 300mg once daily but just recently raised it back to 300x 3 daily because right side discomfort an increase in bilirubin. My headaches and fluid in ears have gotten better, still have the vision issues but heart palpitations have also lessened.
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
Close to five years post liver transplant. No rejections, cyclosporine mono -therapy .Also take 300 mg ursodiol 3x daily for bile duct stricture. Vascular hyper-tensions are becoming a real concern. ie heart, palpitations . fluid in ears , vision problems that aren't related to my actual eyes, the opthamologist confirmed, Migraines that have actually gotten better lately. kidney function is still adequate. My liver is doing very good especially with hep-c..
and the vet will probably prescribe cyclosporine drops to help the eye produce more tears. Before you use the cyclosporine drops, be aware that they will sting your dogs eyes, and long term use may contribute to kidney disease...talk this over with your vet.
Since your dog is 12 years old, please have annual bloodwork done on him to assess liver and kidney functions...bloodwork should be done on all senior dogs.
Best Wishes for you and your dog.....
In an additional 33 patients, glomerular and tubular NEP protein levels from renal graft biopsies were significantly higher among the 13 patients receiving cyclosporine + EC-MPS than among the 12 patients receiving cyclosporine + azathioprine or 8 patients receiving cyclosporine alone. Glomerular NEP expression inversely correlated with glomerulosclerosis and proteinuria, and tubular NEP expression inversely correlated with interstitial fibrosis.
Given that yesterday he said to not take the warfarin he was changing me from the genertic warfarin and putting me on the brand name of the med coumadin. Said some folks do not tolerate warfarin well but do well on coumadin and i am to start the coumadin today. I would be lying if i didn't say i am a bit gunshy at this point. This med has made me absolutely miserable and today is my 43rd bday...
I am currently under St Thomas hospital for this, they are stating I should take Cyclosporine for 6 months, I was wondering if someone on here has taken this treatment and it has worked for them??, I am not convinced on this medication as I have read so many bad things about it.
My consultant has stated that 70% of people whilst on cyclosporine will be clear, one third will have total remission,one third will be same as before, one third will be worse once the treatment has stopped.
We immediately put her on an antibiotic ointment and cyclosporine. It has been almost 10 days and while there is less discharge, she is still having some trouble opening her eye, she just keeps it closed (unless she gets excited). At some times you look at her and she looks completely fine, others times she can barely open her eye. Is this normal for KCS? Should we have seen some major improvement by now?
I was switched to cyclosporine and Myfortic. When the Incivek was started my cyclosporine was dropped to 25 mg once per day due to their interaction. Due to my previous non-response and to the multiple variations of the HCV I carry my odds were considered to be about 30%, maybe 40% at best. At the end of week 4 the HCV RNA was not detectable. The only additional side effect is that the anemia came quicker this time. I will start Procrit injections probably sometime this week.
DOES ANYONE KNOW IF WARFARIN CAN LOWER YOUR BLOOD COUNT AND AND ALSO LOWER CALCIUM AND VITAMIN D LEVELS?
ve tried to read as much as I can about warfarin along the way. I even went to a day-long CEU workshop for medical professionals on warfarin management and got the certificate. But I'm still not an expert. To my way of thinking, the experts are the hematologists, pharmacists, and other health professionals who manage large numbers of people's warfarin on a daily basis.
3 days later (boxing day) I was rushed to hospital with chest pains and diagnosed with self imposed pulmonary embolism. I was put on to Warfarin and monitored in hospital for 2 weeks.
t know how warfarin is affecting your life style. I have been on warfarin for years and had no concerns about running and bike riding, and using power wood working tools. All of these activities puts one at an increased risk of a cut and bleeding, but I simply take the risk. On the other hand, I don't sky dive, or pick fights ....
The most common anticoagulation drug prescribed after heart valve surgery is warfarin (Coumadin). The newer blood thinners are apixaban and dabigatran, also known as Pradaxa and are expensive. The main concern is that specific antidotes for bleeding are available for warfarin but not yet developed for the new drugs.
Hope this helped and do keep us posted.
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