and the vet will probably prescribe cyclosporine drops to help the eye produce more tears. Before you use the cyclosporine drops, be aware that they will sting your dogs eyes, and long term use may contribute to kidney disease...talk this over with your vet.
Since your dog is 12 years old, please have annual bloodwork done on him to assess liver and kidney functions...bloodwork should be done on all senior dogs.
Best Wishes for you and your dog.....
My dog has been treated for dry eyes for a year. She has been on many medications. Tacrolimus, cyclsporine, pilocarpine, neopolydex, gentamycin, tobramycin, simplicef, gabapenten, genteal drops, oint. gel, refresh, blink, now she is also taking tramadol for pain. She has been wearing the hood for 6 months to prevent her for scratching her eyes. She just turned 4 and and she is in so much pain, We finally decided to have surgery and have found out it is 2600.00 per eye.
At first, she was just being treated for conjunctivitis because of the discharge in both eyes. However, after a couple of days we noticed one of her eyes wasn't "glistening" and she was having problems opening it, so we went back to the vet and they did a schirmer? test and came back that she has KCS in her eye. They also did a corneal stain, and showed small a few small ulcers on both eyes. We immediately put her on an antibiotic ointment and cyclosporine.
Close to five years post liver transplant. No rejections, cyclosporine mono -therapy .Also take 300 mg ursodiol 3x daily for bile duct stricture. Vascular hyper-tensions are becoming a real concern. ie heart, palpitations . fluid in ears , vision problems that aren't related to my actual eyes, the opthamologist confirmed, Migraines that have actually gotten better lately. kidney function is still adequate. My liver is doing very good especially with hep-c..
First of all, you want to stay away from products like Artificial Tears and other over-the-counter eye lubricants, because these products contain a form of soap as a stabilizer, and while they are fine for occasional use in normal eyes that just happen to be in a temporarily drying condition, for the lifelong treatment that will be needed for dry eye, the soap stabilizer will be too irritating. There are special preparations that contain cyclosporine that are used to treat KCS.
We have used prescription Optimmune for dry eyes in our 9 yo Westie - it works and there have been no other side-effects/symptoms that I have detected. The stuff is rather expensive, a very small tube is something like $35 - good news is I use only 1/4" of the bead that comes out of the tube (ointment) in each eye. So one tube last about 3 months, maybe a week or two more.
Our vet said non-treatment could result in the dog going blind. He is already deaf, blind too would be too much.
Yes I took Cyclosporine for my aquagenic urticaria, it helped so much but not enough to have a normal life :S but maybe for you its going to be different...
Hi,
I would like to know why you started taking cyclosporine when it is not the first drug that should be taken for collagenous colitis.
Simple antidiarrheals like loperamide or diphenoxylate are to be taken initially for control of symptoms.
If there is no response then other medications like mesalamine, budesonide, immunosuppressants may be tried.
I have been prescribed teva-cyclosporine 0.05%, I was wondering if it is okay to put the eye drops in my eye, and then after like 10 minutes or more use a warm eye compress, I am very stressed due to my bloodshot eyes from dry eye, and I find that the warm compress helps me to fall asleep but do not want to "wash" away or eliminate the effects of the eye drops with the moisture from the warm compress. any thoughts will be appreciated !
Could taking less ursodiol have contributed to my diminishing symptoms. What would be the lest acceptable through cyclosporine level for a patient on mono -therapy four and one half years post transplant with no episodes of rejection? Thank you so very much Dr.
t been approved in Europe. Cyclosporine is only available for oral intake for other purposes...I came across a message of a lady who said it was easier to get cyclosporine drops if you borrowed a dog with dry eyes and took him
to the vet lol.I don't really like the idea of buying off the internet but I'll look into it.My eyes are clearing up and though I'm still stuck at home with fever and sore throat, I'm getting better.Root for me, I really want to use my contacts again!
Your problem could be due to severe dry eyes but that's unusual in a male, most severe dry eyes are females. Could be due to other diseases of the cornea. I don't think I can add anything else from the history you posted.
You can of course get a second opinion from a different eye hospital or consultant.
Hi ! Wow... I had no idea that cyclosporine has been prescribed for various autoimmune diseases and even allergies ! I think it is a shame that many of these wonderful drugs (steriods... Valcyte.... cyclosporine) are immunosuppressants and can have terrible side effects.
I'm happy to hear that researchers are working hard to find cures for these conditions and that they are concerned about the rising numbers of people who have these autoimmune problems.
I use Atopica (Cyclosporine) for my Bulldog and it has been great for him.He has been on all kinds of other meds for his allergies in the past and the Atopica has been the best med of them all.He takes 100mg 2-3 times a week.When he first went on it ,He took it every day for a month then every other day for a month and now he is down to 2-3 a week.His skin was so raw before he went on it.
In an additional 33 patients, glomerular and tubular NEP protein levels from renal graft biopsies were significantly higher among the 13 patients receiving cyclosporine + EC-MPS than among the 12 patients receiving cyclosporine + azathioprine or 8 patients receiving cyclosporine alone. Glomerular NEP expression inversely correlated with glomerulosclerosis and proteinuria, and tubular NEP expression inversely correlated with interstitial fibrosis.
I am currently under St Thomas hospital for this, they are stating I should take Cyclosporine for 6 months, I was wondering if someone on here has taken this treatment and it has worked for them??, I am not convinced on this medication as I have read so many bad things about it.
My consultant has stated that 70% of people whilst on cyclosporine will be clear, one third will have total remission,one third will be same as before, one third will be worse once the treatment has stopped.
Below is one of the medical record of a patient, seek help from ophthalmologist,to see if there is any improvement for the treatment regimen.
Thank you very much!!!
Admission condition: "Found that elevated blood sugar for more than five years, right eye pain for three months". Physical examination on admission showed the following: general condition, VOD:0.5 (correction). Fundus examination of optic nerve papilla edema, conjunctival hyperemia edema slightly.
Doctor John, thank you for explaining to me what each of my medicines is for.
No, I do not wear contacts, but I do wear my glasses when I need them.
My eyes are better now that I'm still on my prescribed medicines.. but unfortunately, they start to itch badly (especially the corners and sometimes the tear ducts) if I delay taking them just an hour or something lol.
I was switched to cyclosporine and Myfortic. When the Incivek was started my cyclosporine was dropped to 25 mg once per day due to their interaction. Due to my previous non-response and to the multiple variations of the HCV I carry my odds were considered to be about 30%, maybe 40% at best. At the end of week 4 the HCV RNA was not detectable. The only additional side effect is that the anemia came quicker this time. I will start Procrit injections probably sometime this week.
My oldest son is 32 in July 2018. He was transplanted 30 years ago with the wrong blood type( He is a O with an A Liver) He has been off all medications since he was 17 years old, so for 13 years. My youngest son who is 28 was transplanted 26 years ago. He got large B-Cell Lymphoma at age 7 from his cyclosporine. He went through CHOP chemotherapy and has been on NO IMMO DRUGS and takes nothing for rejection for over 21 years.
s biopsy and lab numbers clearly show him heading down the road to fibrosis and cirrohsis, would it make sense to push for trying the new drugs at least the approved ones for non-transplant such as teleprevir and bocepavir? Otherwise the patient is looking at another transplant which would seem to be quite a negative option.
t swelling and foamy urine. Now that I have a diagnosis, I am on pill forms of Prednisone every other day and Cyclosporine 2x every day. I have been on the meds for over 1 1/2 weeks and noticed that the foamy urine amount has doubled, my face swells unbelievably, and walking is difficult, as the bottom of my feet and ankles cause me severe pain. I checked with my Nephrologist and she states that it will take a little while for my body to adjust to the medicine.
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