and the vet will probably prescribe cyclosporine drops to help the eye produce more tears. Before you use the cyclosporine drops, be aware that they will sting your dogs eyes, and long term use may contribute to kidney disease...talk this over with your vet.
Since your dog is 12 years old, please have annual bloodwork done on him to assess liver and kidney functions...bloodwork should be done on all senior dogs.
Best Wishes for you and your dog.....
Yes I took Cyclosporine for my aquagenic urticaria, it helped so much but not enough to have a normal life :S but maybe for you its going to be different...
Hi,
I would like to know why you started taking cyclosporine when it is not the first drug that should be taken for collagenous colitis.
Simple antidiarrheals like loperamide or diphenoxylate are to be taken initially for control of symptoms.
If there is no response then other medications like mesalamine, budesonide, immunosuppressants may be tried.
The compound is 1% cyclosporine with corn oil. I get from my vet it's $39.00 for 10 ml. 1 drop in each eye every 12 hours (twice a day). It also comes in a 2% strength. It's not called optimmune, it's a compounded medicine from a company called Wedgewood. My vet said they have used this drug for animals for years, and just recently made "restasis" for humans. Restasis is way more expensive and not the proper strength for dogs. My vet advised against it.
Could taking less ursodiol have contributed to my diminishing symptoms. What would be the lest acceptable through cyclosporine level for a patient on mono -therapy four and one half years post transplant with no episodes of rejection? Thank you so very much Dr.
I know that you said that your dog has been on cyclosporine in the past for the treatment of KCS, however has she ever used a product called 'Optimmune"? It's a preparation that contains cyclosporine but it's different from the cyclosporine drops.
When eyedrop preparations to treat KCS are made up, they have stabilizers put in so that they don't lose their potency too quickly before the whole preparation can be used.
to them, so I took him to the vet, afraid he had a sudden case of SARDS. She said no, tested him for dry eye and gave me Cyclosporine drops.
I have an appointment with an opthmologist who comes to our town once a month on April 2, but now he seems totally blind. Has anyone else dealt with this? Is there any hope for his eyesight? Surgery??
Thanks to anyone who can respond!
Close to five years post liver transplant. No rejections, cyclosporine mono -therapy .Also take 300 mg ursodiol 3x daily for bile duct stricture. Vascular hyper-tensions are becoming a real concern. ie heart, palpitations . fluid in ears , vision problems that aren't related to my actual eyes, the opthamologist confirmed, Migraines that have actually gotten better lately. kidney function is still adequate. My liver is doing very good especially with hep-c..
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
Hi ! Wow... I had no idea that cyclosporine has been prescribed for various autoimmune diseases and even allergies ! I think it is a shame that many of these wonderful drugs (steriods... Valcyte.... cyclosporine) are immunosuppressants and can have terrible side effects.
I'm happy to hear that researchers are working hard to find cures for these conditions and that they are concerned about the rising numbers of people who have these autoimmune problems.
I use Atopica (Cyclosporine) for my Bulldog and it has been great for him.He has been on all kinds of other meds for his allergies in the past and the Atopica has been the best med of them all.He takes 100mg 2-3 times a week.When he first went on it ,He took it every day for a month then every other day for a month and now he is down to 2-3 a week.His skin was so raw before he went on it.
In an additional 33 patients, glomerular and tubular NEP protein levels from renal graft biopsies were significantly higher among the 13 patients receiving cyclosporine + EC-MPS than among the 12 patients receiving cyclosporine + azathioprine or 8 patients receiving cyclosporine alone. Glomerular NEP expression inversely correlated with glomerulosclerosis and proteinuria, and tubular NEP expression inversely correlated with interstitial fibrosis.
I am currently under St Thomas hospital for this, they are stating I should take Cyclosporine for 6 months, I was wondering if someone on here has taken this treatment and it has worked for them??, I am not convinced on this medication as I have read so many bad things about it.
My consultant has stated that 70% of people whilst on cyclosporine will be clear, one third will have total remission,one third will be same as before, one third will be worse once the treatment has stopped.
At first, she was just being treated for conjunctivitis because of the discharge in both eyes. However, after a couple of days we noticed one of her eyes wasn't "glistening" and she was having problems opening it, so we went back to the vet and they did a schirmer? test and came back that she has KCS in her eye. They also did a corneal stain, and showed small a few small ulcers on both eyes. We immediately put her on an antibiotic ointment and cyclosporine.
Below is one of the medical record of a patient, seek help from ophthalmologist,to see if there is any improvement for the treatment regimen.
Thank you very much!!!
Admission condition: "Found that elevated blood sugar for more than five years, right eye pain for three months". Physical examination on admission showed the following: general condition, VOD:0.5 (correction). Fundus examination of optic nerve papilla edema, conjunctival hyperemia edema slightly.
I was switched to cyclosporine and Myfortic. When the Incivek was started my cyclosporine was dropped to 25 mg once per day due to their interaction. Due to my previous non-response and to the multiple variations of the HCV I carry my odds were considered to be about 30%, maybe 40% at best. At the end of week 4 the HCV RNA was not detectable. The only additional side effect is that the anemia came quicker this time. I will start Procrit injections probably sometime this week.
My oldest son is 32 in July 2018. He was transplanted 30 years ago with the wrong blood type( He is a O with an A Liver) He has been off all medications since he was 17 years old, so for 13 years. My youngest son who is 28 was transplanted 26 years ago. He got large B-Cell Lymphoma at age 7 from his cyclosporine. He went through CHOP chemotherapy and has been on NO IMMO DRUGS and takes nothing for rejection for over 21 years.
s biopsy and lab numbers clearly show him heading down the road to fibrosis and cirrohsis, would it make sense to push for trying the new drugs at least the approved ones for non-transplant such as teleprevir and bocepavir? Otherwise the patient is looking at another transplant which would seem to be quite a negative option.
Believe me, i want to get rid of the cats. But i don't even mess with them. They're my husband's cats. He takes care of them i do not. They just like to annoy me. I honestly only take care of my dog, turtles, and our fish. But like i said, there's absolutely no animals allowed in my baby's room. None have ever gone in there and probably won't ever go in there. I'm keeping my baby away from the animals for quite a while.
Or, explain how you are feeling and ask your partner to step up to the plate with her. For him to do more to care for the dog and have the dog fall more under his responsibilities. AND< perhaps a good dog trainer would be in order. A dog should go to the bathroom outside only and learn manners and if you tell them to sit and stay that they do it. so, I'd get some dog training for your pooch to see if that helps.
My dog is one of the joys of my life.
Are your cat's in heat
Anyone else feel so much closer to their animals now? I have a 8 month old kitten and before I got pregnant she didn't want anything to do with me, now she's constantly all over me and if any body squirts her with the spray bottle I get extremely defensive and she's always wanting to be near/on my belly. Just wondering if anyone else is going through this?
Does anyone else have any animals that are glued to them?
I am sure some of you have animals. I have a sweet black cat and a tiny chihuahua that is a bit crazy. My boyfriend wants to get rid of them before the baby gets here which I think is ridiculous honestly. I have had these two their whole lives and they are my first children. He is worried about them not adjusting to or hurting the baby which I understand but on the other hand I am aware there will be an adjustment period just like we have.
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