Erythromycin and clindamycin can be used in both
topical creams and oral prescriptives. The oral forms of these are antibiotics for severe
acne. Since bacteria are able to build resistance to antibiotics, however, erythromycin and clindamycin, though safe, may not be very effective.
Despite general belief that oral contraceptive pills for acne will harm the baby if continued, there is no evidence showing women to be at a higher risk for defects.