For patients with early cirrhosis (CPT class A or B), the use of acetaminophen is safe as long as the recommended
dose is not exceeded (1,000 mg per
dose, repeated no more often than every 6 hours). Patients with more advanced cirrhosis should take only ½ of the recommended dose. In fact, for patients with cirrhosis, acetaminophen, when used as described, is the preferred medication for the treatment of pain.