Avisg, thanks for answering my question, but do you know if that is true both ways? Like, Ultram while on Sub, and Sub while on Ultram? No induction time? Believe me, if I had known the reason that Sub probably isn't good for Ultram, I think I would have tried tapering first. The problem is that I cannot afford the Sub doctor as it is, and I can't afford any more medication. What I have is Sub, and Tramadol, and I am really worried about having a seizure.