Pre-medicating before your injection was helpful to me and I always took it at night, to try
and sleep through most
side-
effects. For others, like myself, the
side-
effects did not go away or even lessen over time and after three years, I finally gave up on the drug. I understand that is fairly rare. But I can tell you, that Avonex worked wonders for keeping me stable and free of relapses, even for a few years after stopping the drug. My MRI's didn't worsen for almost 5 years.