avonex titration

I had been on Avonex since diagnosis but decided to make the switch to Tecfidera so I no longer had to do injections. I lasted approximately a week and a half. I had stomach pain and nausea which progressed to vomiting and diarrhea when I stopped taking titer dose and took full dose. My doctor decided to have me go back to titer dose and stay on it for a full month before taking full strength. Has anyone else tried this and did it work??

I have MS and I'm on venlafaxine, but for pre-existing depression. I can't really speak to it in the context it's been prescribed for you, but I do recommend a slow titration of the dose. I remember starting out and getting pretty nauseous on 75mg. The reduced me to 37.5mg and then slowly raised it to the 112.5mg I've been on for a few years now.

DX on 2/14...started Avonex last week with nurse helping and did fine. This week I thought I did okay but noticed the plunger did not go completely down. It was the 1/2 dose. Since I am inclined to over analyze, trying not to panic. Figure I'll be taking more next week...but since you all seem like you know your stuff...thought I'd ask the experts. Thanks.

For those that take Avonex, how bad have the flu like symptoms been for you? I had been on Copaxone and just recently stopped because I have had it with the huge welts and lumps the size of eggs. I am tempted to just take a see how it goes attitude since my MS seems to be mild and not do the DMD's for the time being. My neuro brought up Avonex and told me about the flu like symptoms and I don't know if that or the welts and lumps are worse?

Hi I have a question- I have been on Copaxone for over 10 years and I am suffering with indented sites which can no longer let my shots be injected. My question is which of the ms treatments should I go to next? My MS dr. gave me papers on Avonex but the side effects is what I'm worried about. My Copazone has worked so well I'm afraid to change but just running out of places to give the shot. Thanks for any reply's..

The first time I took Avonex I was SO poorly just like you. I now take pain relief from lunch time and take the injection at 18.00 and I normally sleep through the side effects. Also it takes time for your body to get used to it.

She has told me to stop my copaxone, and to go and get the antibiotics for my infection, and wait for a month, and she wants me to start Avonex *sp* , so, I am going to start investigating this one, she did not want me to go the route of the chemo yet, and wants to try the avonex first. So, hoping this will happen, without me having to be the police on my case !!! LOL I am still waiting for the new specialist appt, about my bladder , and hoping it will be sooner than later.

Started Rebif almost a month ago (after being on Avonex for over a year, blah) and this week has come and gone and Aunt Flo is absent this month. Now since I was 12 there have only been a handfull of times this has happened: Getting pregnant with child #1 and Child #2 and also there was a 3 month time frame in 2007 (in the summer leading up to my initial flare up). Also my tubes have been tied, burnt , you name it it was done..

Rebif, Avonex, Copaxone, Betaserone and Extavia are all first line of defense drugs. Rebif and Extavia and Avonex are the same drug. Avonex is the smallest dose but the biggest needle. Extavia is a larger dose than Rebif, simply because it is every other day, as Rebif is 3x a week. Copaxone is the most compatable with your natural body and has the least side effects, but is a daily injection . The key is to get on ANY med therapy and keep going.

I did get flu-like symptoms that included headache, slight fever, some aches and pains, etc. But, with REbif the give you a titration dosing schedule which makes you barely feel them coming on and they were very bearable for me. They will monitor the chance of it affecting your liver and blood cell counts. I've been fine so far. I took advil, tylenol or naproxen right before bed so I could sleep through any possible symptoms and it worked.

I read your post to me about how you don't like block/replace therapy, and that you like MMI titration, what is that? HOw do you keep your patients from going hypo thyroid on only ATD's? and if they do go hypo, how do you help them if you don't use replacement? Also, does using ATD's burn out your thyroid? and does replacement burn out your thyroid? Do you consider 5mg of MMI to be a high dose of ATD?

Can anyone tell me what is a Oxygen Titration test is about I will be having this tes on 4/9/08. It kinda scare me a little bit. What will they be doing for me doing this Titration.

i have posted something similar not too long ago- as my -additional- problem is recurrent major depression for more than 10 years so far.

Has anyone else experienced some incredible, ever-lasting bruising at their injection sites? I've been on a titration dose for about 5 weeks now and I can still see the the bruise from my first injection. A majority of the other injection sites are red blotches that are about 2 inches in diameter. These marks are mostly visible on my thighs and stomach. Sometimes I get a little residual pain and a red welt.

Hi, I was recently diagnosed with MS and had my first Avonex injection Friday. Friday night was tough (fever, chills, pain and eventually heavy sweating) but I felt pretty good by Saturday morning. Saturday afternoon I started feeling kind of down and by Sunday morning I feel even more so. I can't decide if this is a result of the drug or just the situation as a whole.

Sigh, I have a question from a friend. She would like to know if avonex causes calcium deficiency? She is diagnosed with ms. Not like me.

Is anyone on avonex? My dr. wants to switch me to avonex, but with having lupus, I really don't want to go on an interferon. I'm on copaxone, now but because I have large welts on my arms he wants to switch me. I don't want to switch. Do I have the right to deny a new medication I feel would be detrimental to me?

Flu-like symptoms are a fairly common side effect during the initial weeks of Avonex treatment. It is recommended that you take your Avonex injection before bedtime. Immediately before your injection, and for the 24 hours that follow the injection, patients have found that use of over the counter pain and fever reducing medications can help with this common side effect." You could also get on the Avonex website for further info. good luck. hope that you feel better soon.

I have been on copaxone for little over a year its not working for me so my neuro has asked me to try avonex. My avonex nurse is coming this evening but I am wondering how long you actually gave it to get the symptoms of the shot to calm down. I am crossing everything to hope I dont get the flu symptoms so bad but we will see. I have a husband that works away and 3 small kids to care for, I dont want to be in bed all weekend when its the only time we get to spend as a family.

Hi guys, has anyone not heard from the AVONEX people once they were put on it.??? I have heard from heath nurses, and today, got my WELCOME package, but still no product. I don't know what is going on, and of course the lady or the rep from Avonex is away on holidays till the 2nd. of Dec..... so, I guess we will do it next week ... Just to let you guys know, they stopped my antiobiotic IV today, and said that it was an MS attack. Wherever there are nerves, MS can strike.

Hi Candy, When I was on the Avonex I had terrible itchy skin. I would start scratching and I would well up from the scratching. I also found that it dried out my skin as well. I use pure coconut oil right out of the shower then gold bond lotion right over the top of the oil. It seems to be helping tremendously. The oil soaks in quickly and the lotions seems to seal in the moisture. I hope this helps. Sorry you have this to deal with on top of everything else.

//www.themcfox.com/multiple-sclerosis/ms-drugs/avonex/avonex-blood-counts.htm updated 2004, it might be worth finding out if your having a negative reaction and need to change DMD.

I've been on Avonex for 2.5 years and it's suited me well but I have just had a 4 week break. I then took my injection on Tuesday night and was strangely fine on Wednesday and Thursday but on Friday, Saturday and today I have lost about 50% of my strength from my left arm and leg. Is this likely to be a side effect from restarting the Avonex (muscle weakness) or a relapse?

Avonex titration

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