In 2011, the agency voiced concerns that taking the drugs long-term may actually make bones weaker and increase the risk of rare but serious side effects such as atypical fractures of the thigh bone, esophageal cancer and osteonecrosis of the jaw, a rare but painful condition in which the jaw bone crumbles. To investigate, the FDA reviewed data from women who had taken the drugs for six to 10 years.
s flare, severe nausea, loss of appetite, weight loss of 18 lbs in last 6 weeks,steatorrhea, pain in mid chest and right upper quadrant. Had CT scan 2 weeks ago which showed significant inflammation in terminal ileum and old pancreatitis with calcification. Gastroscopy last week showed oesphagitis.Biopsies taken. MRI scan Nov 2007 showed two strictures in small intestine. Gastro has advised following until I see him in clinic 23 July:
Double my mtx injections to 25 mg weekly.
I took my first dose of Alendronate and then experience significant muscle pain for the next 4 days. Does anyone know if I should expect this to happen each time I take it or is it something to happen for the first few times until my body adjusts to the medicine?
Do you mean Fosamax (alendronate)? If you do, its for treating bone problems like Osteoperosis by adding bone mass and slows bone loss. I use it for Osteopenia.
5 centimeter supra-orbital bone tumor that has been completely stable on scans since 3 and 1/2 years ago. I have had a continuous intractable headache behind my forehead which has not responded to the usual headache therapy regimen. It is believed to be monostotic fibrous dysplasia of the skull. I have found articles to suggest that high-dose bisphosphonate therapy (40 mg/day for 6 months) offers a significant improvement in patients with fibrous dysplasia of the skull.
I also have recurrant Ovarian Cancer, and Crohn's Disease. What medications are you on other than B12 injections? I have found many of the other medications I take other than chemo make my hair fall out. I am currently not taking IV chemo, but still losing hair. I guess I've gotten used to hats, but look forward to the day I don't need them!
As I had a full hysterectomy some 19 yrs ago, I could go straight on to Arimidex. Yes, estrogen does fuel cancer cells, and after ovary removal, the body does still make small amounts, mostly from the adrenal glands on top of the kidneys Both tamoxifen and AI's block oestrogen to the breast cells, but in different ways. I would consult again with your doctors about oopherectomy and be clear in your own mind why they do not want to remove your ovaries.
Hope all goes well for you.
Liz.
thankyou,i am with contact of my doctor ,he said there is no solution for damaged vertibras,but calcium and vitiman d and alendronate sodium/cholecaiciferol tablets will help spine and bones from further damages but what to do with prednisones i cant stop them because of asthma and taking of them will damage other bones isnt there any other solution instead of prednisones, i know there is nothing accept these because my doctor told me:(
Osteoporosis is definitely not a cancer. The bones become weak and brittle and subject to fractures.
A common cause is use of oral steroids such as prednisone in excess of three months.
The bright spot is there are several treatment options to include parathyroid hormone and zoldronic acid.
I don't have enough knowledge to suggest a specific treatment protocol, however this is definitely something you should discuss with your primary care physician.
For my bones I take Calcium+vitamin D, and once weekly Novo Alendronate which is the equivalent of what you are taking now.My surgeon told me that it's very important for me to take Arimidex because it lessens considerably the estrogen that the body produces thus diminishing the chances of recurrence or developing a new tumor.Personally I would prefer not taking any drugs, but since I have very little side effects, I will continue taking this medication for the next 4 years.
Osteoporosis medications like Raloxifene (Evista), alendronate (Fosomax), risendronate (Actonel) and ibandronate (Boniva) all can cause flu like symptoms in individuals that are taking them. I am not sure what medications you are on, but this could be your problem.
Hi, I asked a question previously. I have a 3.5 x 2.5 cm supra-orbital bone tumor that is believed to be fribrous dysplasia. I began having an intractable pressure headache behind my forehead which became worse just over 3 years ago, and this is what lead to a brain scan. Since it's discovery in 2005, the tumor has remained completely unchanged. I have the monostotic disease.
Thank you. Interestingly enough, my gyno referred me to the pharmacist and the pharmacist couldn't tell me anything I didn't already know from the internet- so-- if you would be kind enough to offer your opinion - ..... if the mechanism of action is to decrease osteoclasts (thereby dead bone cells are not removed) - is this helpful to have denser bones made of dead bone tissue?
Bitter taste in the mouth or saliva can be caused by a variety of issues including gastrointestinal conditions such as acid reflux, gum or dental problems, side effect of medications and even hormonal causes. If it persists, consult your dentist and attending physician for initial evaluation. Take care and do keep us posted.
Also, would it perhaps be possible to add some alendronate, or something else to help her bone density and still be able to benefit from the thyroid medication? Thank you so much!
Studies have indeed show that high blood glucose may predispose to cancer and cancer cells primarily run on glucose. Views on this are diverse and while further studies may need to be done, it is still up to the patient to take this. Westernized approach of cancer has involved chemotherapy and medications while eastern medicine have been employing dietary approach in management of diseases for a long time. Discuss this with your doctors for proper management. Take care and best regards.
I am afraid of the idea of having penile cancer but am only 18 and the last time I had sex was 3.5 months ago. I have have had a painless red rash around my urethra and part of the head of the penis for almost 2 months. I'm worried because STD tests came back negative so I'm wondering if it is HPV that has manifested it into a cancer?
I could be mistaken - but I have looked the evidence over and talked with people here and the theory of RAI and cancer you talk about is reversed. I as an RAI patients back in 2003 was recently informed by an ENT that people that do have RAI - that develop nodules are at a higher risk on the nodule being carcimona. That is not very enlightening for me b/c they found I do have a solid nodule now.
I am on Armour - no there is no blood. //// yuckie.....
Graves speeds up your body.
I think it would be best to google and get informed about sugar's effect upon cancer--as there are numerous and valid studies that are contrary to the doctor's response, here. my oncologist agrees that cancer indeed likes sugar and thrives on it. sugar also suppresses the immune system..
there are so many varied opinions--and each is subjective. you must go within to find the answer that is right for YOU--it's your body, your life.
She refused, and saw another doctor who helped with treatments while pregnant. She got rid of the cancer and gave birth to my cousin! Today, my cousin is 18 years old and perfectly healthy! And technology has changed a lot since then! Hopefully your friend has just as good of doctors...so sorry she is going through this, I wish her the best! Cancer has hit my family hard in the past recent months, I know how hard it can be.
My family immediately went into action because, unknown to me, ovarian cancer runs in my family. I have a great-aunt who died on my mothers side and every other female since has had hysterectomies after pre-cancerous cells, tumors and solid cysts were found. On my father side my aunt became infertile at a young age due to pre-cancerous tumors on her ovaries and had them removed at age 30. My grandmother also had to have a hysterectomy for the same reasons.
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