After about 3 months, was having bad low back pain and pain on the top of both thighs. I then had a left rib fracture of unknown cause. At that time, no side effects
like this were published. I did find a small group with similar symptoms but my Doc said it was not the Nexium. I stopped it and within 4 days, the flank and thigh pain were gone. I was later put on Omeprazole, 40 mg 2x a day fir the past few months. Not sure yet, but my low back muscles are killing me.