therefore clinically significant disease most frequently occurs as an opportunistic infection in
those with a weak immune system, such as small children
, the elderly, and the immunocompromised.
Nocardia may also cause a variety of cutaneous infections such as actinomycetoma (especially Nocardia brasiliensis), lymphocutaneous disease, cellulitis and subcutaneous abscesses.
Antibiotic therapy with a sulfonamide, most commonly trimethoprim-sulfamethoxazole, is the treatment of choice.