Diagnosis, however, according to the McDonald criteria, requires objective evidence of lesions disseminated in time and space which may be seen with MRI
. Typical MRI
results for MS is
involvement of corpus callosum, U fibers, temporal lobes, brainstem, cerebellum and spinal cord. It is important to differentiate the nature of the white matter lesions- whether this is due to normal aging or from vascular issues. It is good that the initial evaluation has ruled this out.