Mostly myoclonus is one of several signs in a wide variety of nervous system disorders such as Multiple sclerosis, Parkinson's disease, Alzheimer's disease, Subacute sclerosing panencephalitis and
Creutzfeldt-Jakob disease (CJD), SLE ( systemic lupus erythematosus) and
some forms of epilepsy. It may also result from infection, head or spinal cord injury, stroke, brain tumors, kidney
or liver failure
, lipid storage disease, chemical or drug poisoning, as a side effect of certain drugs (e.g.