I have debilitating fatigue due to MS and have tried everything - Provigil
, Amantadine, Adderall
, Ritalin - the works. While Provigil
helped for some time while I was still working, that was many years ago and its effectiveness eventually petered out. At the time, I was taking a very large dose in accordance to doctor's orders, and my side effects (heart palpitations, increased rate of speech, crashing, etc.) were quite bothersome.