1] using pre-appointment sedation as prescribed by M.D.;
2] telling the dentist, "NO EPINEPHRINE, PLEASE."
"Epi," as it is called, is usually mixed with the local lidocaine to minimize bleeding, prevent allergic reaction, and prolong the effects of the lido local. Epi, which is actually a form of adrenaline, can trigger a physiological 'rush' that is uncomfortable to some.