Some of them have tried other anti nausea meds and Zofran seems to work for most people. I have used it to manage nausea after chemo treatments.
Zofran
Why is this medication prescribed?
Zofran (ondansetron) is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists.
Serotonin has many effects in the body and has several receptors where it can bind. Zofran blocks serotonin at a specific type of receptor (the 5-HT3 receptor)."
http://cancer.emedtv.com/zofran/zofran.html
So you can see that it is best to take it as a preventative and not to wait until after he is already nauseated. Once he is on it for a few doses he should feel better and less nauseated. It does not have to be taken with food.
Taking zofran can cause birth defects, and a serious, life threatening reaction in the mother, called serotonin syndrome. My PCP told me today to use it sparingly, if I can't stop using it in entirety.
http://www.****.com/fertility_cares_blog/fda-warns-against-zofran-use-in-pregnancy/
This is just 1 of the articles that I read that talks about this.
s or selective serotonin reuptake inhibitors and SNRIs, serotonin and norepinephrine reuptake inhibitors do not actually increase the amount of serotonin molecules in the brain. SSRI’s are thought to block the reabsorption (reuptake) of serotonin by certain nerve cells in the brain. This theoretically leaves more serotonin available in the brain. However if you have low serotonin to begin with these medications either will not work well, or work for a while then "poop out".
Has anyone used Remeron for depression, while taking Maxalt for their migraines? I have migraines about every other day, and take 5mg maxalt for them. I was just given Remeron for depression, as the doc said i cannot take any SSRI's because of serotonin syndrome. I cannot find and interactions for Remeron, but just wondering if anyone else has tried these together. Any info appreciated.
I take 8 mg every 8 hours and I take it about an hour before I plan to eat and take my pills. Zofran blocks the chemicals that cause the nausea.
"It is likely that Zofran works in the small intestine, but it may also work in the brain. The medication blocks serotonin, a chemical produced by the body that is associated with nausea and vomiting. Serotonin has many effects in the body and has several receptors where it can bind.
In the brain without an ssri the body breaks down used serotonin with an enzyme and then makes more. With an ssri serotonin is directed to targeted receptor sites, which differ depending on the medication, and breakdown is prevented so the serotonin washes around longer in the targeted sites. Other sites, in turn, shut off because the brain doesn't see them as necessary anymore. You have the same amount of serotonin, it's just hanging around longer in the targeted receptors.
Thanks so much for the info. I'm glad to hear you do not stop making serotonin and I know to go slow. I'm now at 2mg and still cutting slowly. It will take me quite a while to get to nothing. I have been working at this for about 2 years.
Just in case you think I'm nuts, it is precisely because I stopped prozac at under 4 mg and it threw me into the worst depression I have ever known that I am going so slowly. Plus I have had a few events that had to put dropping on hold.
There's no evidence anyone has more or less serotonin than anyone else. What ssris do is prevent the breakdown of serotonin so it soaks the neuron longer in it. This isn't the natural way the body acts, but these meds have helped many people. But whether you want to take them or not, or need them or not, is up to you. They won't cure you, they will only mitigate the symptoms you're having. If there is a cure, it's through therapy.
If that does not work, then you probably need a prescription for Zofran which blocks the nausea and vomiting (which is caused by the drugs). Many of us used Zofran. It works very well for most of us. I took 8 mg every 8 hours for a few months.
Don't let this go. It will snowball. If the phenergan does not work, then ask for Zofran. Zofran does not make you sleepy. Phenergan does. Phenergan is cheaper, but Zofran works better (in my opinion). It is used to treat the nausea from Chemo.
If you took something else that increased serotonin, it could be dangerous, and cause what is called Serotonin Syndrome, which can be fatal.
For that reason, amino acid remedies for opiate withdrawal symptom relief
such as 5HTP and SAM-E, and anything else that may have a simular effect must be avoided.
It can also cause sexual dysfunction. But it can also prevent premature ejaculation problems. Hey I'm not thinking that! LoL!
Klonopin is a benzo as other have said.
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