My current dose is Prograf 3 mg AM/ Prograf 3 mg PM and Rapamune 4 mg AM. The intent is to convert me to 100% Rapamune because of the nephro-toxicity of the Prograf and my young age and because of the anti-cancer properties of Rapamune. Data, while horribly limited, has shown Rapamune's anti-cancer properties have had success against vascular tumors such as mine so EHE, in this case chronic, is part of the cancers Rapamune affects (some cancers it has no effect).
This is so individual that it is hard to know what level is right for anyone without a lot of experience. I think 6.5 is nothing to worry about. I might ask his coordinator if she thinks the gap between this Prograf level and his previous level looks alright. I wonder whether his Prograf dose was the same for both labs and, if so, whether the lab time was different or if there was some other factor present.
What is considered "high blood pressure" and when does it become a concern??? My typical blood pressure is in the low 120's/low 130's however, lately its been in the mid140's/low 150's. Does this happen after transplant (3 months post transplant)? Should I be concerned?
Does Prograf cause tremors? And...can these tremors be contributing to making a person feel tired and exhausted???
If i lower my prograf lower than 6.5 through rate i start getting discomfort right side .i am having cognitive issues on prograf that are getting very hard to live with, seems like it got alot worse after my last of three mri with contrast in two years. was hospitalized two days after last contrast exsposure white blood count went to1000, headach, fever urine got exstremly foamy, severe itching ,tighting and rashd eveloped on lower legs two weeks after.
You are still a relatively new transplant. It is not unusual for Prograf levels to fluctuate a lot early on. That is why you have blood test fairly frequently. I imagine you are having them at least once per week, no? After about 5 months post TP, the prograf level should be more stable, and is desireable to be at 3 to 8. I wouldn't worry about the numbers you have, just talk to the Dr. with any concerns.
My doctor told me there are many foods that are being tested to see what there reaction is when Prograf is used by a transplant recipient. The new foods being tested are all citrus fruits. Pomegranate and apricots are now being studied to see if they have the same effect as grapefruit juice, (increasing Prograf levels). My doctors advise to me is, "If you eat something and later don't feel well, don't eat it again." Listen to your body.
The doctor - does he suspect virus infection, I am not sure - prescribed a blood test, result of which comes out after a week or so. Is this situation - TLC at 2.8 for two weeks now despite CellCept being reduced to Nil mg - is so serious a problem as to cause worry? I am not sure how serious is this is - I am not doctor.
I went into rejection twice in the hospital and because of this my transplant team saw it best to put me on 5mg of prograf twice a day as well as 4 mg of rapimune, which by the way was off label and i had to sign a release form for. Just within the past 2 months they lowerd my dosage of rapimune to 2mg but kept the prograf the same. My question to you is exactly how suppressed is my immune system?
My history: liver transplant 1 year ago, had 2 moderate rejections and 1 mild since transplant. At present time having moderate rejection, recently had one portal stent and 8 Bilary ERCP's to remove stones and sludge and had stenting done, and at the present time there are no blockages. Was on Rapamune (5mg a day) prior to hernia surgery and then week before hernia surgery was put on Prograf (4mg a day) and taken off the Rapamune. I have been on Progaf since hernia surgery (8 weeks ago).
My husband had a liver transplant on Aug.5th - and has been **** well. Today he broke out in hives all over his head. He is itching terribly - and the 2nd Benadryl hasn't helped. He is on Cellcept, prograf, and is in a clinical trial (so we don't really know what the extra meds are). Should we be concerned???
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