Because retinal detachment is serious and may result in permanent vision loss, it was essential to duplicate the Canadian findings—particularly given the widespread prescribing
of quinolones. To my knowledge, the first attempt to confirm this
association appears in this issue of JAMA.3 Using data from Danish national registries, Pasternak and colleagues3 performed a cohort study of nearly 750 000 episodes of oral fluoroquinolone use and more than 5.