how can i get doctor to prescribe tarceva for inoperable lung cancer with secondary brain cancer has recieved one chemo session for lung then 5 radiotherapy for brain...help??????
4 rounds of chemo of taxotere and cisplatin seem to have not worked as now he has mets in his liver, bones and adrenal glands. His doctor is aftraid that Tarceva is not recommended to someone with mets to the bone. That is not what I read. Can you please let me know if Tarceva is for him and whether that can hep stop or slow down the disease?
Thanks.
since then the diesies showed improvment and shrinkage in tumor. . HE has been under maintance treatment with Tarceva since 2009 upto now. the previous PET-CT ON JULY 2011 WAS NEGATIVE AND CONCLUSION was that no evidence of residual hypermetabolic disease seen in lung.. but the recent CT showed smal new lesion 1,8 *2 cm. in comparison to previous.and his new PET -CT in TURKEY hospital FN shows new FDG(+)SUV max:5) pulmonary nodule in the lower lobe of the lung.
If the node is positive for cancer metastases, this may imply disease progression in spite of Tarceva intake. Tarceva may have to be replaced with another more effective chemotherapy drug. Radiation therapy to shrink the node and relieve the swelling may also have to be done. Consult with your oncologist as soon as possible so you can be properly assessed.
Thanks for your response. To clarify: his treatment was adjunctive. At the time they saw no sign of cancer outside the lung. Now, however, after 4 rounds of chemotherapy the disease seems to have spread during treatment with taxotere and cisplatin: it's now in the liver, bones and adrenal glands. His original tumor was EGFR positive that is why Tarceva came up as a viable second step.
m doing research as quickly as I can to help she and her husband make an informed decision about what to do...if anything. The local drs are recommending 4 weeks of full brain radiation followed by tarceva. Prior to the finding the mets, they were planning 6 weeks of radiation to the right lung in combination with etoposide and cisplatin.
I'd appreciate any feedback. My thanks in advance to all responses....
She has done very well with chemo and radiation until recently. She was started on Tarceva about 3 weeks ago. Recently, she has been experiencing a lot of confusion. I cannot find anywhere that this is a side effect of Tarceva (it is the only drug she is on at this time). Is it possible that she has a brain metastases? If not, what are the likely causes.
My husband was diagnosed with a Pancoast tumor on his lung. He went thru chemo/ radiation and finally had surgery to remove the tumor. It was successful. He had more chemo for precaution. After one year, the cancer came back into his Adrenal Gland. It is also in his Lymph Nodes. They put him on Tarceva( a pill he took everyday) And after 6-7 weeks, he had tests done which showed it didn't do anything.. the tumor has grown. They said there is no other options..
At the time of the procedure it messured 1.3 cm at the time of being placed on Tarceva the measurment 1.9 cm with in three wks after surgery in April.
Placed on Tarceva the first of May and No incress in growth...Doctors say Stable Remission...Now I have been told that I have a Mass on the back side of my thyroid gland on the left side. We have tried ultra sound guided needle biopsy...didn't work.
Now the docs say they want to try a Core Biopsy?
He has been through several chemo and radiation treatments and is now starting on Tarceva. It has been a long road so far and he has his good days and bad days. I don't think there's any way even the doctors can tell us how much time they have left specifically. His doctor said it could be a year, 5 or even 10, but of course we are all hoping and praying for at least 20 more with him.
It has already spread to the spine, both lungs and the lymph system. Doctors triede Tarceva for 3 weeks but her body had a very bad reaction. For the spine they did radiotherapy. But since she was diagnose 3 months ago she has lost aalmost her voice. she is using oxygen for the major part of the day but doctors don't wan't to talk about time. no more medes will be given and she was reffer to hospice....
There are pharmaceuticals used to treat Psoriasis, but these involve suppressing the immune system to help with the body attacking its own skin. These are still experimental or at least relatively new pharmaceuticals. I don't have Psoriasis myself, so I don't know much about the pharmaceuticals for it. I do see commercials for one that has been promoted, but I hate to say anything about it, since I've never used it.
Tibotec Pharmaceuticals Limited, Ireland
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited
Information provided by: Tibotec Pharmaceuticals Limited, Ireland
ClinicalTrials.gov Identifier: NCT00703118
Another clinical trial announcement but does anyone know of USA sites for this one or similar trial?
Oh my God! Thank you Lord for letting me hear from someone with darn near my situation!
I had lower left lobectomy May 29, 2009. Stage 1A BAC (nodule 1.3 cm)...no chemo (there seems to be only one that "might" work, Tarceva) and no radiation (what will they burn out? the lobe's gone already).
90 % "chance" of making 5 years is what they tell me. Mucho NO info on BAC. Only bad prognosis.
I have already survived breast cancer (BRCA 2 Mutation) for 6 YEARS!
And, I tend to avoid pharmaceuticals as much as possible. Many pharmaceuticals cause more harm than good.
Have you tried things like digestive enzymes? That's the only natural suggestion I can think of right off hand. You might want to try posting your question in Complimentary Medicine. Some of the people there are very knowledgeable about these things.
http://finance.yahoo.com/news/arrowhead-pharmaceuticals-initiates-phase-1-113000233.html;_ylc=X1MDMTE5Nzc4NDE4NQRfZXgDMQRfeXJpZAM5djF2ZW50YmxpbDJhBGcDZFhWcFpEeHVjejQyWVRRNU16STNaaTA1T1dabExUTm1aV1F0T0RSbFl5MHdNRE14TXpFME1HWmpNbVk4Wm1sbGJHUStZWEozY2c9PQRsYW5nA2VuLVVTBG9yaWdfbGFuZwNlbgRvcmlnX3JlZ2lvbgNVUwRwb3MDMARyZWdpb24DVVMEc3ltYm9sA0FSV1I-?.
I have never had any patients complain of this.
Dr. O.
Arrowhead Pharmaceuticals Doses First Patient with Hepatitis B in Multiple Ascending Dose Portion of Phase 1/2 Study of ARC-521
http://www.businesswire.
I think the AMN stands for the manufacture.
He started Tarceva this January but it seems it did not work as the cancer spread to brain…. 9 mets were identified in the initial MRI 2 weeks ago but the subsequent MRI right before yesterday’s gamma knife procedure (which removed 7 mets) evidenced numerous other tiny/small tumors spread all over the brain….He has been in relatively good condition (eating well, no weight loss) until these new mets emerged (which affected his walking and reading ability)….
In lung cancer, there are assays for quantitative testing of epidermal growth factor receptors (EGFR), which confers sensitivity to some drugs used in lung cancer like Iressa or Tarceva. The cost of testing can range from a few hundred dollars (e.g. ER/ PR assays) to around 3800 dollars for the Oncotype DX test.
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