The standard therapy options include intravenous immunoglobulin and plasmapharesis, corticosteroids, azathioprine, cyclophosphamide, etanercept, mycophenolate mofetil, interferon alpha 2a and tacrolimus. Current ones are interferon beta 1a, rituximab, and high dose cyclophosphamide. Your neurologist needs to apprise you of the long-term side effects since prolonged therapy are required. Botox shots are not known to be used in therapy.
My opth has diagnosed me with blepharitis, I use sterilid w/ compresses and take flaxseed oil, and I also use preservative free eyedrops for moisture. However nothing has worked to my satisfaction besides tobradex which I've used for about a year and half- my eyelid inflammation is pretty severe even with the other treatments, however w/ tobradex my symptoms are almost nonexistent.
i wouldnt lower the tacrolimus dose further
(interestingly though, a few days before at the vet, the schirmer test was 12 in both eyes). Now 6 weeks later, the right eye has a 6 and the left eye still has 0. The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus.
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
I lost my insurance after 13 years post-transplant.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
i would be extremely cautious about using it until more data is available especially since its purported effects on tacrolimus and cyclosporine metabolism are extreme. i am quite confident that there will be clinical trials coming down the road extremely soon.
Yes I have been worked up by a neurologist, I have seen many doctors and received several diagnosis, some conflicting, but neuropathy is what seems to match my symptoms the most. I have been checked for diabetes and MANY other things, all normal. I do not drink alcohol at all, or take drugs.
Antihistaminics, topical steroids, PUVA therapy, retinoic acid and tacrolimus are the available treatment options for lichen planus.It is best to clarify your doubts by your dermatologist. I hope it helps.
Take care and regards!
My tacrolimus level is 4.2 after 4 months of liver transplant, Is it dangerous? what should i do?
Please get your vitamin B levels done and try some vitamin B tablets or shots. There are other causes for neuropathy, to read about it do visit website
http://en.wikipedia.
I am taking Tacrolimus 3mg and Myfortic 360mg twice a day, FK level is around 5. Am I going to take these two immunosuppressants (probably same dosages) for life or might be reducing the dosage ?
There are several causes of small fiber neuropathy, including diabetes, vitamin deficiencies, autoimmune problems
The other type of sensory neuropathy is called a large fiber neuropathy. There are several categories of this type of neuropathy, and there are many many causes. Sensory neuropathies can involve just one nerve or several nerves in the body. Some types of sensory neuropathies occur and progress very slowly, others sort of wax and wane (with flare-ups) and some are progressive.
Can tacrolimus eye drops and Cyclosporine ointment cause cancer in dogs? My precious dog, baby and best friend was diagnosed just last week with Transitional Cell Carcinoma in his bladder. It is a rapid growing cancer. I am completely heartbroken and am wondering if there was something I could've done to prevent this. He has been on these two eye medications for about a year. His name is Duke and he is a beautiful tri-colored collie and is a little over 10 years old.
I have MS and Neuropathy. I am currently on Tysabri. Previously I was on Betaseron and IVIG. When I went to Tysabri my doctor took me off IVIG and now my Neuropathy is worse, my feet and legs are on fire. Does any one know if it is safe to be on Tysabri and IVIG at the same time? My doctor said she would need to consult with other doctors before she would add IVIG to my treatment.
Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
If still the symptoms do not improve then please get a clinical examination done by a dermatologist.
I hope it helps. Take care and please do keep me posted in case you have any additional doubts. Kind regards.
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